AIMC Topic: Knowledge Bases
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The implementation of knowledge-based planning with partial OAR contours for prostate radiotherapy.
Journal of applied clinical medical physics
Feb 7, 2025
PURPOSE: Intra- and inter-observer contour uncertainty is a continuous challenge in treatment planning for radiotherapy. Our proposed solution to address this challenge is the use of partial contours for treatment planning, focusing on uninvolved or ...
Systematic collection, annotation, and pattern analysis of viral vaccines in the VIOLIN vaccine knowledgebase.
Frontiers in cellular and infection microbiology
Feb 7, 2025
BACKGROUND: Viral vaccines have been proven significant in protecting us against viral diseases such as COVID-19. To better understand and design viral vaccines, it is critical to systematically collect, annotate, and analyse various viral vaccines a...
The use of multiple evidence base methods to enrich climate change research and knowledge in the Arctic.
Ambio
Jan 25, 2025
Indigenous and local knowledge (ILK) is increasingly used along with scientific knowledge (SK) to understand climate change. The multi evidence base (MEB) offers ways of combining knowledge systems together. Nonetheless, there is little guidance on h...
Multi-institutional Knowledge-Based (KB) plan prediction benchmark models for whole breast irradiation.
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Jan 16, 2025
PURPOSE: To train and validate KB prediction models by merging a large multi-institutional cohort of whole breast irradiation (WBI) plans using tangential fields.
Leveraging Transformers-based models and linked data for deep phenotyping in radiology.
Computer methods and programs in biomedicine
Jan 3, 2025
BACKGROUND AND OBJECTIVE: Despite significant investments in the normalization and the standardization of Electronic Health Records (EHRs), free text is still the rule rather than the exception in clinical notes. The use of free text has implications...
Can knowledge-based planning models validated on ethnically diverse patients lead to global standardisation of external beam radiation therapy for locally advanced cervix cancer?
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 19, 2024
BACKGROUND AND PURPOSE: Knowledge-based planning (KBP) can consistently and efficiently create high-quality Volumetric Arc Therapy (VMAT) plans for cervix cancer. This study describes the cross-validation of two KBP models on geographically distinct ...
Validating knowledge-based volumetric modulated arc therapy plans with a multi-institution model (broad model) using a complete open-loop dataset for prostate cancer.
Physical and engineering sciences in medicine
Dec 18, 2024
This study examined the characteristics of the broad model (KBP) through a complete open-loop evaluation of volumetric modulated arc therapy (VMAT) plans for prostate cancer in 30 patients at two institutions. KBP, trained using 561 prostate cancer V...
Contrasting Multi-Source Temporal Knowledge Graphs for Biomedical Hypothesis Generation.
IEEE/ACM transactions on computational biology and bioinformatics
Dec 10, 2024
Hypothesis Generation (HG) aims to expedite biomedical researches by generating novel hypotheses from existing scientific literature. Most existing studies focused on modeling static snapshots of the corpus, neglecting the temporal evolution of scien...
KGRACDA: A Model Based on Knowledge Graph from Recursion and Attention Aggregation for CircRNA-Disease Association Prediction.
IEEE/ACM transactions on computational biology and bioinformatics
Dec 10, 2024
CircRNA is closely related to human disease, so it is important to predict circRNA-disease association (CDA). However, the traditional biological detection methods have high difficulty and low accuracy, and computational methods represented by deep l...
An assessment of the influence of trade-off optimization in commercial knowledge based planning library creation for tongue cancer patients.
Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Dec 6, 2024
This article aims to compare the dosimetric performance between knowledge-based plan (KBP) libraries with and without trade-off (TO) exploration using multicriterial optimization (MCO) for tongue cancer patients. The trade-off optimized library (KBP_...
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