AIMC Topic: Liposomes
Clear Filters Showing 21 to 30 of 38 articles
Identification of Immune Signatures of Novel Adjuvant Formulations Using Machine Learning.
Scientific reports
Nov 30, 2018
Adjuvants have long been critical components of vaccines, but the exact mechanisms of their action and precisely how they alter or enhance vaccine-induced immune responses are often unclear. In this study, we used broad immunoprofiling of antibody, c...
Neurotoxicity of intraneural injection of bupivacaine liposome injectable suspension versus bupivacaine hydrochloride in a porcine model.
Veterinary anaesthesia and analgesia
Oct 11, 2018
OBJECTIVE: To test whether neurotoxic effects of a bupivacaine liposome injectable suspension differ from those of a standard formulation of bupivacaine hydrochloride (HCl) after intraneural injection into the sciatic nerves in pigs.
Comparison of response surface methodology and artificial neural network to optimize novel ophthalmic flexible nano-liposomes: Characterization, evaluation, in vivo pharmacokinetics and molecular dynamics simulation.
Colloids and surfaces. B, Biointerfaces
Aug 23, 2018
To improve the topical delivery of pilocarpine hydrochloride (PN) to treat glaucoma, flexible nano-liposomes containing PN (PN-FLs) were prepared, optimized and characterized. Artificial neural network (ANN) and response surface methodology (RSM) wer...
Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens.
Molecules (Basel, Switzerland)
Dec 20, 2017
The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, includin...
Humans
Anti-Bacterial Agents
Microbial Sensitivity Tests
Oils, Volatile
Drug Resistance, Multiple, Bacterial
Cell Survival
Drug Resistance, Multiple, Fungal
Naphthoquinones
Rhizopus
Tracheophyta
Umbilical Veins
Liposomes
Drug Synergism
Erythrocytes
Endothelial Cells
Plant Oils
Candida
Antifungal Agents
Highly sensitive colorimetric aptasensor for ochratoxin A detection based on enzyme-encapsulated liposome.
Analytica chimica acta
Nov 27, 2017
A simple, low-cost, and sensitive liposome-based colorimetric aptasensor has been developed to detect ochratoxin A (OTA). Specifically, a dumbbell-shaped probe was designed, including magnetic beads (MBs), double-stranded DNA (dsDNA), and enzyme-enca...
Nano-biotinylated liposome-based immunoassay for the ultrasensitive detection of protein biomarker in urine.
Talanta
Nov 21, 2017
With the development of proteomics and the continuous discovery of biomarkers of trace proteins, it is important to accurately quantify low abundance protein, especially in urine for clinical diagnostics. In this paper, we reported a novel nano-bioti...
Artificial neural networks as alternative tool for minimizing error predictions in manufacturing ultradeformable nanoliposome formulations.
Drug development and industrial pharmacy
Oct 17, 2017
This work was aimed at determining the feasibility of artificial neural networks (ANN) by implementing backpropagation algorithms with default settings to generate better predictive models than multiple linear regression (MLR) analysis. The study was...
Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes.
IEEE transactions on nanobioscience
Jan 30, 2017
The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in part, due to the drop in concentration of chemothe...
RSM and ANN modeling-based optimization approach for the development of ultrasound-assisted liposome encapsulation of piceid.
Ultrasonics sonochemistry
Nov 14, 2016
Piceid, a naturally occurring derivative of resveratrol found in many plants, has recently been considered as a potential nutraceutical. However, its poorly water-soluble property could cause a coupled problem of biological activities concerning drug...
Preparation, Characterization, and Antitumor Activities of Miriplatin-Loaded Liposomes.
Journal of pharmaceutical sciences
Dec 22, 2015
Because of the insolubility of miriplatin in water, miriplatin and lipiodol suspension is the sole formulation of miriplatin approved in Japan to treat hepatocellular carcinoma by transcatheter arterial chemoembolization. Until now, there have been n...
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