AIMC Topic: Extracellular Fluid

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CXCL12 impact on glioblastoma cells behaviors under dynamic culture conditions: Insights for developing new therapeutic approaches.

PloS one
Glioblastoma multiforme (GBM) is the most prevalent malignant brain tumor, with an average survival time of 14 to 20 months. Its capacity to invade brain parenchyma leads to the failure of conventional treatments and subsequent tumor recurrence. Rece...

Predicting intratumoral fluid pressure and liposome accumulation using physics informed deep learning.

Scientific reports
Liposome-based anticancer agents take advantage of the increased vascular permeability and transvascular pressure gradients for selective accumulation in tumors, a phenomenon known as the enhanced permeability and retention(EPR) effect. The EPR effec...

Improved Perceptual Learning by Control of Extracellular GABA Concentration by Astrocytic Gap Junctions.

Neural computation
Learning of sensory cues is believed to rely on synchronous pre- and postsynaptic neuronal firing. Evidence is mounting that such synchronicity is not merely caused by properties of the underlying neuronal network but could also depend on the integri...

Micropore array-based SERS sensor assisted by convolutional neural networks for subsurface biotoxic-free detection of interstitial fluid in bioassays.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Accurate and sensitive detection of small-molecule metabolites such as uric acid, glucose, and lactic acid is critical in biomedical diagnostics and clinical applications. Traditional detection methods often face limitations such as complex procedure...