AIMC Topic: Longitudinal Studies

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Development and Validation of a Lifestyle-Based 10-Year Risk Prediction Model of Colorectal Cancer for Early Stratification: Evidence from a Longitudinal Screening Cohort in China.

Nutrients
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, with growing evidence linking risk to lifestyle and dietary factors. However, nutrition-related exposures have rarely been integrated into existing CRC ...

Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States.

Frontiers in public health
BACKGROUND: Juvenile idiopathic arthritis (JIA) is a prevalent chronic rheumatological condition in children, with reported prevalence ranging from 12. 8 to 45 per 100,000 and incidence rates from 7.8 to 8.3 per 100,000 person-years. The diagnosis of...

Inflammatory biomarkers as predictors for unlocking antidepressant efficacy: Assessing predictive value and risk stratification in major depressive disorder in a prospective longitudinal study.

Journal of affective disorders
BACKGROUND: Major depressive disorder (MDD) is characterized by significant heterogeneity in treatment response, with inflammation hypothesized to play a role in its pathophysiology. Peripheral inflammatory biomarkers, such as the neutrophil-to-lymph...

Machine learning models of depression in middle-aged and older adults with cardiovascular metabolic diseases.

Journal of affective disorders
BACKGROUND: The incidence of cardiovascular metabolic diseases (CMD) is increasing, and depression in CMD patients significantly impacts prognosis. Therefore, this study aimed to develop and validate a predictive model for depression in CMD patients ...

Study protocol for the Rainbow Austrian Longitudinal Family (RALF) study: a longitudinal, multi-method, multi-rater investigation of risk and resilience factors in Austrian LGBTQ+ parent families.

BMC psychology
BACKGROUND: Research on LGBTQ+ parent families is evolving to include a growing range of family systems, identities, methodologies, and topics. However, studies that examine minority-specific risk and resilience factors and their associations with wi...

Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.

Frontiers in public health
BACKGROUND: This study investigated the cost-effectiveness and clinical impact of the 3E model (education, empowerment, and economy) in diabetes management using advanced machine learning techniques.

[Cluster predictors of trajectories of leisure-time physical activity intensity in men and women from ELSA-Brasil].

Cadernos de saude publica
The maintenance of physical activity over time is a challenge for public health. Predictors of different physical activity intensities have not been sufficiently analyzed. This study aimed to identify clusters of trajectories of physical activity int...

Using Machine Learning to Predict Cognitive Decline in Older Adults From the Chinese Longitudinal Healthy Longevity Survey: Model Development and Validation Study.

JMIR aging
BACKGROUND: Cognitive impairment, indicative of Alzheimer disease and other forms of dementia, significantly deteriorates the quality of life of older adult populations and imposes considerable burdens on families and health care systems worldwide. T...

Exploring the potential and limitations of deep learning and explainable AI for longitudinal life course analysis.

BMC public health
BACKGROUND: Understanding the complex interplay between life course exposures, such as adverse childhood experiences and environmental factors, and disease risk is essential for developing effective public health interventions. Traditional epidemiolo...

Development and validation of a machine learning risk prediction model for asthma attacks in adults in primary care.

NPJ primary care respiratory medicine
Primary care consultations provide an opportunity for patients and clinicians to assess asthma attack risk. Using a data-driven risk prediction tool with routinely collected health records may be an efficient way to aid promotion of effective self-ma...