OBJECTIVES: To extract intratumoral, peritumoral, and integrated intratumoral-peritumoral CT radiomic features, develop multi-source radiomic models using various machine learning algorithms to identify the optimal model, and integrate clinical facto...
Cancer imaging : the official publication of the International Cancer Imaging Society
Mar 12, 2025
PURPOSE: This study aimed to select robust features against lung motion in a phantom study and use them as input to feature selection algorithms and machine learning classifiers in a clinical study to predict the lymphovascular invasion (LVI) of non-...
BACKGROUND: Early and accurate identification of epidermal growth factor receptor (EGFR) mutation status in non-small cell lung cancer (NSCLC) patients with brain metastases is critical for guiding targeted therapy. This study aimed to develop a deep...
Diseases of the airways and the other parts of the lung cause chronic respiratory diseases. The major cause of lung disease is tobacco smoke, along with risk factors such as dust, air pollution, chemicals, and frequent lower respiratory infections du...
. Tracking tumors with multi-leaf collimators and x-ray imaging can be a cost-effective motion management method to reduce internal target volume margins for lung cancer patients, sparing normal tissues while ensuring target coverage. To realize that...
BACKGROUND: To evaluate the clinical applicability of deep learning (DL) models based on automatic segmentation in preoperatively predicting tumor spread through air spaces (STAS) in peripheral stage I lung adenocarcinoma (LUAD).
PURPOSE: This is a preliminary analysis of one of the secondary endpoints in the prospective study cohort. The aim of this study is to assess the image quality and diagnostic confidence for lung cancer of CT images generated by using cadmium-zinc-tel...
BACKGROUND AND OBJECTIVE: Spread through air spaces (STAS) is an important factor in determining the aggressiveness and recurrence risk of lung cancer, especially in early-stage adenocarcinoma. Preoperative identification of STAS is crucial for optim...
The quantification of circulating tumour DNA (ctDNA) in blood enables non-invasive surveillance of cancer progression. Here we show that a deep-learning model can accurately quantify ctDNA from the density distribution of cell-free DNA-fragment lengt...
European journal of cancer (Oxford, England : 1990)
Mar 6, 2025
Lung cancer screening implementation has led to expanded imaging of the chest in older, tobacco-exposed populations. Growing numbers of screening cases are also found to have CT-detectable emphysema or elevated levels of coronary calcium, indicating ...
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