AIMC Topic: Lung Neoplasms

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Robust vs. Non-robust radiomic features: the quest for optimal machine learning models using phantom and clinical studies.

Cancer imaging : the official publication of the International Cancer Imaging Society
PURPOSE: This study aimed to select robust features against lung motion in a phantom study and use them as input to feature selection algorithms and machine learning classifiers in a clinical study to predict the lymphovascular invasion (LVI) of non-...

Deep learning radiomics for the prediction of epidermal growth factor receptor mutation status based on MRI in brain metastasis from lung adenocarcinoma patients.

BMC cancer
BACKGROUND: Early and accurate identification of epidermal growth factor receptor (EGFR) mutation status in non-small cell lung cancer (NSCLC) patients with brain metastases is critical for guiding targeted therapy. This study aimed to develop a deep...

Lung cancer detection with machine learning classifiers with multi-attribute decision-making system and deep learning model.

Scientific reports
Diseases of the airways and the other parts of the lung cause chronic respiratory diseases. The major cause of lung disease is tobacco smoke, along with risk factors such as dust, air pollution, chemicals, and frequent lower respiratory infections du...

Validation of patient-specific deep learning markerless lung tumor tracking aided by 4DCBCT.

Physics in medicine and biology
. Tracking tumors with multi-leaf collimators and x-ray imaging can be a cost-effective motion management method to reduce internal target volume margins for lung cancer patients, sparing normal tissues while ensuring target coverage. To realize that...

Prediction of tumor spread through air spaces with an automatic segmentation deep learning model in peripheral stage I lung adenocarcinoma.

Respiratory research
BACKGROUND: To evaluate the clinical applicability of deep learning (DL) models based on automatic segmentation in preoperatively predicting tumor spread through air spaces (STAS) in peripheral stage I lung adenocarcinoma (LUAD).

CZT-based photon-counting-detector CT with deep-learning reconstruction: image quality and diagnostic confidence for lung tumor assessment.

Japanese journal of radiology
PURPOSE: This is a preliminary analysis of one of the secondary endpoints in the prospective study cohort. The aim of this study is to assess the image quality and diagnostic confidence for lung cancer of CT images generated by using cadmium-zinc-tel...

Prediction of STAS in lung adenocarcinoma with nodules ≤ 2 cm using machine learning: a multicenter retrospective study.

BMC cancer
BACKGROUND AND OBJECTIVE: Spread through air spaces (STAS) is an important factor in determining the aggressiveness and recurrence risk of lung cancer, especially in early-stage adenocarcinoma. Preoperative identification of STAS is crucial for optim...

A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths.

Nature biomedical engineering
The quantification of circulating tumour DNA (ctDNA) in blood enables non-invasive surveillance of cancer progression. Here we show that a deep-learning model can accurately quantify ctDNA from the density distribution of cell-free DNA-fragment lengt...

AI integrations with lung cancer screening: Considerations in developing AI in a public health setting.

European journal of cancer (Oxford, England : 1990)
Lung cancer screening implementation has led to expanded imaging of the chest in older, tobacco-exposed populations. Growing numbers of screening cases are also found to have CT-detectable emphysema or elevated levels of coronary calcium, indicating ...