AIMC Topic: Machine Learning

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Multi-parametric MRI phenotype with trustworthy machine learning for differentiating CNS demyelinating diseases.

Journal of translational medicine
BACKGROUND: Misdiagnosis of multiple sclerosis (MS) and neuromyelitis optica (NMO) may delay the treatment, resulting in poor prognosis. However, the precise identification of these two diseases is still challenging in clinical practice. We aimed to ...

Machine learning - Predicting Ames mutagenicity of small molecules.

Journal of molecular graphics & modelling
In modern drug discovery, detection of a compound's potential mutagenicity is crucial. However, the traditional method of mutagenicity detection using the Ames test is costly and time consuming as the compounds need to be synthesised and then tested ...

Applying interpretable deep learning models to identify chronic cough patients using EHR data.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Chronic cough (CC) affects approximately 10% of adults. Many disease states are associated with chronic cough, such as asthma, upper airway cough syndrome, bronchitis, and gastroesophageal reflux disease. The lack of an ICD ...

Ensemble based machine learning approach for prediction of glioma and multi-grade classification.

Computers in biology and medicine
Glioma is the most pernicious cancer of the nervous system, with histological grade influencing the survival of patients. Despite many studies on the multimodal treatment approach, survival time remains brief. In this study, a novel two-stage ensembl...

A machine learning-based biological aging prediction and its associations with healthy lifestyles: the Dongfeng-Tongji cohort.

Annals of the New York Academy of Sciences
This study aims to establish a biological age (BA) predictor and to investigate the roles of lifestyles on biological aging. The 14,848 participants with the available information of multisystem measurements from the Dongfeng-Tongji cohort were used ...

Biologically motivated learning method for deep neural networks using hierarchical competitive learning.

Neural networks : the official journal of the International Neural Network Society
This study proposes a novel biologically motivated learning method for deep convolutional neural networks (CNNs). The combination of CNNs and backpropagation learning is the most powerful method in recent machine learning regimes. However, it require...

Identifying the predictive effectiveness of a genetic risk score for incident hypertension using machine learning methods among populations in rural China.

Hypertension research : official journal of the Japanese Society of Hypertension
Current studies have shown the controversial effect of genetic risk scores (GRSs) in hypertension prediction. Machine learning methods are used extensively in the medical field but rarely in the mining of genetic information. This study aims to deter...

Skin lesion image retrieval using transfer learning-based approach for query-driven distance recommendation.

Computers in biology and medicine
Content-Based Dermatological Lesion Retrieval (CBDLR) systems retrieve similar skin lesion images, with a pathology-confirmed diagnosis, for a given query image of a skin lesion. By producing an intuitive support to both inexperienced and experienced...

Machine Learning for Real-Time Heart Disease Prediction.

IEEE journal of biomedical and health informatics
Heart-related anomalies are among the most common causes of death worldwide. Patients are often asymptomatic until a fatal event happens, and even when they are under observation, trained personnel is needed in order to identify a heart anomaly. In t...

A Review of Recent Work in Transfer Learning and Domain Adaptation for Natural Language Processing of Electronic Health Records.

Yearbook of medical informatics
OBJECTIVES: We survey recent work in biomedical NLP on building more adaptable or generalizable models, with a focus on work dealing with electronic health record (EHR) texts, to better understand recent trends in this area and identify opportunities...