BACKGROUND: Alzheimer's disease (AD) is a complex progressive neurodegenerative disorder commonly characterized by short term memory loss. Presently no effective therapeutic treatments exist that can completely cure this disease. The cause of Alzheim...
Journal of computational biology : a journal of computational molecular cell biology
Oct 17, 2016
Discriminating native-like structures from false positives with high accuracy is one of the biggest challenges in protein-protein docking. While there is an agreement on the existence of a relationship between various favorable intermolecular interac...
The Q-UEL language of XML-like tags and the associated software applications are providing a valuable toolkit for Evidence Based Medicine (EBM). In this paper the already existing applications, data bases, and tags are brought together with new ones....
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Oct 17, 2016
PURPOSE: To predict patients who would benefit from adaptive radiotherapy (ART) and re-planning intervention based on machine learning from anatomical and dosimetric variations in a retrospective dataset.
With the rapid growth of biomedical literature, a large amount of knowledge about diseases, symptoms, and therapeutic substances hidden in the literature can be used for drug discovery and disease therapy. In this paper, we present a method of constr...
Neural networks : the official journal of the International Neural Network Society
Oct 14, 2016
In this paper, we introduce a fast linear dimensionality reduction method named incremental orthogonal component analysis (IOCA). IOCA is designed to automatically extract desired orthogonal components (OCs) in an online environment. The OCs and the ...
IEEE/ACM transactions on computational biology and bioinformatics
Oct 13, 2016
In extreme cold weather, living organisms produce Antifreeze Proteins (AFPs) to counter the otherwise lethal intracellular formation of ice. Structures and sequences of various AFPs exhibit a high degree of heterogeneity, consequently the prediction ...
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Oct 13, 2016
The objective of this pilot study was to test the feasibility of automating the detection of abdominal free fluid in focused assessment with sonography for trauma (FAST) examinations. Perihepatic views from 10 FAST examinations with positive results ...
Magnetic resonance in chemistry : MRC
Oct 11, 2016
Proton magnetic resonance spectroscopy is a powerful noninvasive technique that complements the structural images of cMRI, which aids biomedical and clinical researches, by identifying and visualizing the compositions of various metabolites within th...
Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease, with large variation in survival between patients. Currently, it remains rather difficult to predict survival based on clinical parameters alone. Here, we set out to use clin...
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