AIMC Topic: Machine Learning

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A prediction model of blood pressure for telemedicine.

Health informatics journal
This paper presents a new study based on a machine learning technique, specifically an artificial neural network, for predicting systolic blood pressure through the correlation of variables (age, BMI, exercise level, alcohol consumption level, smokin...

Detecting hospital-acquired infections: A document classification approach using support vector machines and gradient tree boosting.

Health informatics journal
Hospital-acquired infections pose a significant risk to patient health, while their surveillance is an additional workload for hospital staff. Our overall aim is to build a surveillance system that reliably detects all patient records that potentiall...

Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach.

The Journal of pharmacology and experimental therapeutics
Statistical analysis was performed on physicochemical descriptors of ∼250 drugs known to interact with one or more SLC22 "drug" transporters (i.e., SLC22A6 or OAT1, SLC22A8 or OAT3, SLC22A1 or OCT1, and SLC22A2 or OCT2), followed by application of ma...

Large scale deep learning for computer aided detection of mammographic lesions.

Medical image analysis
Recent advances in machine learning yielded new techniques to train deep neural networks, which resulted in highly successful applications in many pattern recognition tasks such as object detection and speech recognition. In this paper we provide a h...

Decoding post-stroke motor function from structural brain imaging.

NeuroImage. Clinical
Clinical research based on neuroimaging data has benefited from machine learning methods, which have the ability to provide individualized predictions and to account for the interaction among units of information in the brain. Application of machine ...

Ensemble based adaptive over-sampling method for imbalanced data learning in computer aided detection of microaneurysm.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Diabetic retinopathy (DR) is a progressive disease, and its detection at an early stage is crucial for saving a patient's vision. An automated screening system for DR can help in reduce the chances of complete blindness due to DR along with lowering ...

Revealing disease-associated pathways by network integration of untargeted metabolomics.

Nature methods
Uncovering the molecular context of dysregulated metabolites is crucial to understand pathogenic pathways. However, their system-level analysis has been limited owing to challenges in global metabolite identification. Most metabolite features detecte...

Adaptive local learning in sampling based motion planning for protein folding.

BMC systems biology
BACKGROUND: Simulating protein folding motions is an important problem in computational biology. Motion planning algorithms, such as Probabilistic Roadmap Methods, have been successful in modeling the folding landscape. Probabilistic Roadmap Methods ...

Batch Mode TD($\lambda$ ) for Controlling Partially Observable Gene Regulatory Networks.

IEEE/ACM transactions on computational biology and bioinformatics
External control of gene regulatory networks (GRNs) has received much attention in recent years. The aim is to find a series of actions to apply to a gene regulation system making it avoid its diseased states. In this work, we propose a novel method ...

Using machine learning to predict radiation pneumonitis in patients with stage I non-small cell lung cancer treated with stereotactic body radiation therapy.

Physics in medicine and biology
To develop a patient-specific 'big data' clinical decision tool to predict pneumonitis in stage I non-small cell lung cancer (NSCLC) patients after stereotactic body radiation therapy (SBRT). 61 features were recorded for 201 consecutive patients wit...