AIMC Topic: Machine Learning

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Texture analysis in gel electrophoresis images using an integrative kernel-based approach.

Scientific reports
Texture information could be used in proteomics to improve the quality of the image analysis of proteins separated on a gel. In order to evaluate the best technique to identify relevant textures, we use several different kernel-based machine learning...

A class of joint models for multivariate longitudinal measurements and a binary event.

Biometrics
Predicting binary events such as newborns with large birthweight is important for obstetricians in their attempt to reduce both maternal and fetal morbidity and mortality. Such predictions have been a challenge in obstetric practice, where longitudin...

UbiSite: incorporating two-layered machine learning method with substrate motifs to predict ubiquitin-conjugation site on lysines.

BMC systems biology
BACKGROUND: The conjugation of ubiquitin to a substrate protein (protein ubiquitylation), which involves a sequential process--E1 activation, E2 conjugation and E3 ligation, is crucial to the regulation of protein function and activity in eukaryotes....

Predicting transcription factor site occupancy using DNA sequence intrinsic and cell-type specific chromatin features.

BMC bioinformatics
BACKGROUND: Understanding the mechanisms by which transcription factors (TF) are recruited to their physiological target sites is crucial for understanding gene regulation. DNA sequence intrinsic features such as predicted binding affinity are often ...

Drug repositioning for non-small cell lung cancer by using machine learning algorithms and topological graph theory.

BMC bioinformatics
BACKGROUND: Non-small cell lung cancer (NSCLC) is one of the leading causes of death globally, and research into NSCLC has been accumulating steadily over several years. Drug repositioning is the current trend in the pharmaceutical industry for ident...

Diagnosing Parkinson's Diseases Using Fuzzy Neural System.

Computational and mathematical methods in medicine
This study presents the design of the recognition system that will discriminate between healthy people and people with Parkinson's disease. A diagnosing of Parkinson's diseases is performed using fusion of the fuzzy system and neural networks. The st...

Modality-independent representations of small quantities based on brain activation patterns.

Human brain mapping
Machine learning or MVPA (Multi Voxel Pattern Analysis) studies have shown that the neural representation of quantities of objects can be decoded from fMRI patterns, in cases where the quantities were visually displayed. Here we apply these technique...

Neural Network-Based DOBC for a Class of Nonlinear Systems With Unmatched Disturbances.

IEEE transactions on neural networks and learning systems
In this brief, the problem of composite anti-disturbance tracking control for a class of strict-feedback systems with unmatched unknown nonlinear functions and external disturbances is investigated. A disturbance-observer-based control (DOBC) in comb...

Representation learning for mammography mass lesion classification with convolutional neural networks.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: The automatic classification of breast imaging lesions is currently an unsolved problem. This paper describes an innovative representation learning framework for breast cancer diagnosis in mammography that integrates deep le...

A Fast Reduced Kernel Extreme Learning Machine.

Neural networks : the official journal of the International Neural Network Society
In this paper, we present a fast and accurate kernel-based supervised algorithm referred to as the Reduced Kernel Extreme Learning Machine (RKELM). In contrast to the work on Support Vector Machine (SVM) or Least Square SVM (LS-SVM), which identifies...