AIMC Topic: Machine Learning

Clear Filters Showing 4561 to 4570 of 34417 articles

MDTL-ACP: Anticancer Peptides Prediction Based on Multi-Domain Transfer Learning.

IEEE journal of biomedical and health informatics
Anticancer peptides (ACPs) have emerged as one of the most promising therapeutic agents for cancer treatment. They are bioactive peptides featuring broad-spectrum activity and low drug-resistance. The discovery of ACPs via traditional biochemical met...

Semantic-Enhanced Graph Contrastive Learning With Adaptive Denoising for Drug Repositioning.

IEEE journal of biomedical and health informatics
The traditional drug development process requires a significant investment in workforce and financial resources. Drug repositioning as an efficient alternative has attracted much attention during the last few years. Despite the wide application and s...

TARSL: Triple-Attention Cross-Network Representation Learning to Predict Synthetic Lethality for Anti-Cancer Drug Discovery.

IEEE journal of biomedical and health informatics
Cancer is a multifaceted disease that results from co-mutations of multi biological molecules. A promising strategy for cancer therapy involves in exploiting the phenomenon of Synthetic Lethality (SL) by targeting the SL partner of cancer gene. Since...

An optimized machine learning framework for predicting and interpreting corporate ESG greenwashing behavior.

PloS one
The accurate prediction and interpretation of corporate Environmental, Social, and Governance (ESG) greenwashing behavior is crucial for enhancing information transparency and improving regulatory effectiveness. This paper addresses the limitations i...

Controlling nutritional status score predicts posthepatectomy liver failure: an online interpretable machine learning prediction model.

European journal of gastroenterology & hepatology
BACKGROUND AND AIMS: Posthepatectomy liver failure (PHLF) remains a severe complication after hepatectomy for hepatocellular carcinoma (HCC) and accurate preoperative evaluation and predictive measures are urgently needed. We investigated the impact ...

Development of Machine Learning Models for Predicting Radiation Dermatitis in Breast Cancer Patients Using Clinical Risk Factors, Patient-Reported Outcomes, and Serum Cytokine Biomarkers.

Clinical breast cancer
BACKGROUND: Radiation dermatitis (RD) is a significant side effect of radiotherapy experienced by breast cancer patients. Severe symptoms include desquamation or ulceration of irradiated skin, which impacts quality of life and increases healthcare co...

A unified approach to medical image segmentation by leveraging mixed supervision and self and transfer learning (MIST).

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Medical image segmentation is important for quantitative disease diagnosis and treatment but relies on accurate pixel-wise labels, which are costly, time-consuming, and require domain expertise. This work introduces MIST (MIxed supervision, Self, and...

Metabolic reprogramming and machine learning-guided cofactor engineering to boost nicotinamide mononucleotide production in Escherichia coli.

Bioresource technology
Nicotinamide mononucleotide (NMN) is a bioactive compound in NAD(P) metabolism, which exhibits diverse pharmaceutical interests. However, enhancing NMN biosynthesis faces the challange of competing with cell growth and disturbing intracellular redox ...

Utilizing Machine Learning Techniques to Predict Negative Remodeling in Uncomplicated Type B Intramural Hematoma.

Annals of vascular surgery
BACKGROUND: To evaluate the effectiveness of machine learning (ML) techniques in predicting negative remodeling in uncomplicated Stanford type B intramural hematoma (IMHB) during the acute phase.

StackTHP: A stacking ensemble model for accurate prediction of tumor-homing peptides in cancer therapy.

Computers in biology and medicine
The tumor-homing peptides (THPs) have emerged as one of the attractive resources for targeted cancer therapy, being able to bind and penetrate tumor cells selectively while ignoring adjacent healthy tissues. Therefore, the computational models to pre...