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ESMAC BEST PAPER 2017: Using machine learning to overcome challenges in GMFCS level assignment.

Gait & posture
We used the random forest classifier to predict Gross Motor Function Classification System (GMFCS) levels I-IV from patient reported abilities recorded on the Gillette Functional Assessment Questionnaire (FAQ). The classifier exhibited outstanding ac...

Learning Doctors' Medicine Prescription Pattern for Chronic Disease Treatment by Mining Electronic Health Records: A Multi-Task Learning Approach.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Increasing learning ability from massive medical data and building learning methods robust to data quality issues are key factors toward building data-driven clinical decision support systems for medicine prescription decision support. Here, we attem...

Drug repositioning for prostate cancer: using a data-driven approach to gain new insights.

AMIA ... Annual Symposium proceedings. AMIA Symposium
UNLABELLED: Prostate cancer (PC) is the most common cancer and the third leading cause of cancer death in men worldwide. Despite its high incidence and mortality, the likelihood of a cure is low for late-stages of PC. There is an unmet need for more ...

A Multi-scale U-Net for Semantic Segmentation of Histological Images from Radical Prostatectomies.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Gleason grading of histological images is important in risk assessment and treatment planning for prostate cancer patients. Much research has been done in classifying small homogeneous cancer regions within histological images. However, semi-supervis...

Classifying Acute Ischemic Stroke Onset Time using Deep Imaging Features.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Models have been developed to predict stroke outcomes (e.g., mortality) in attempt to provide better guidance for stroke treatment. However, there is little work in developing classification models for the problem of unknown time-since-stroke (TSS), ...

Mining Electronic Health Records to Extract Patient-Centered Outcomes Following Prostate Cancer Treatment.

AMIA ... Annual Symposium proceedings. AMIA Symposium
The clinical, granular data in electronic health record (EHR) systems provide opportunities to improve patient care using informatics retrieval methods. However, it is well known that many methodological obstacles exist in accessing data within EHRs....

Inferring Clinical Correlations from EEG Reports with Deep Neural Learning.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Successful diagnosis and management of neurological dysfunction relies on proper communication between the neurologist and the primary physician (or other specialists). Because this communication is documented within medical records, the ability to a...

Calibration Drift Among Regression and Machine Learning Models for Hospital Mortality.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Advanced regression and machine learning models can provide personalized risk predictions to support clinical decision-making. We aimed to understand whether modeling methods impact the tendency of calibration to deteriorate as patient populations sh...