AIMC Topic: MicroRNAs
Clear Filters Showing 121 to 130 of 363 articles
Synchronous Mutual Learning Network and Asynchronous Multi-Scale Embedding Network for miRNA-Disease Association Prediction.
Interdisciplinary sciences, computational life sciences
Feb 4, 2024
MicroRNA (miRNA) serves as a pivotal regulator of numerous cellular processes, and the identification of miRNA-disease associations (MDAs) is crucial for comprehending complex diseases. Recently, graph neural networks (GNN) have made significant adva...
Predicting miRNA-Disease Associations by Combining Graph and Hypergraph Convolutional Network.
Interdisciplinary sciences, computational life sciences
Jan 29, 2024
miRNAs are important regulators for many crucial biological processes. Many recent studies have shown that miRNAs are closely related to various human diseases and can be potential biomarkers or therapeutic targets for some diseases, such as cancers....
Isolation and characterization of exosome-enriched urinary extracellular vesicles from Dent's disease type 1 Spanish patients.
Nefrologia
Jan 28, 2024
BACKGROUND AND OBJECTIVES: Dent's disease type 1 (DD1) is a rare X-linked hereditary pathology caused by CLCN5 mutations that is characterized mainly by proximal tubule dysfunction, hypercalciuria, nephrolithiasis/nephrocalcinosis, progressive chroni...
miTDS: Uncovering miRNA-mRNA interactions with deep learning for functional target prediction.
Methods (San Diego, Calif.)
Jan 26, 2024
MicroRNAs (miRNAs) are vital in regulating gene expression through binding to specific target sites on messenger RNAs (mRNAs), a process closely tied to cancer pathogenesis. Identifying miRNA functional targets is essential but challenging, due to in...
DiCleave: a deep learning model for predicting human Dicer cleavage sites.
BMC bioinformatics
Jan 9, 2024
BACKGROUND: MicroRNAs (miRNAs) are a class of non-coding RNAs that play a pivotal role as gene expression regulators. These miRNAs are typically approximately 20 to 25 nucleotides long. The maturation of miRNAs requires Dicer cleavage at specific sit...
Influences of microRNA-451 on the expression of HMGB1 in myocardial cells and its mechanism in ischemia-reperfusion injury.
Cellular and molecular biology (Noisy-le-Grand, France)
Dec 31, 2023
This work aimed to understand the underlying mechanism of micro-ribonucleic acid (MicroRNA) (miR)-451 in ischemia-reperfusion injury (IRI) and the influences of miR-451 on high mobility group box 1 protein (HMGB1) in myocardial cells, 30 specific pat...
A Machine Learning Approach for Highlighting microRNAs as Biomarkers Linked to Amyotrophic Lateral Sclerosis Diagnosis and Progression.
Biomolecules
Dec 29, 2023
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord. The early diagnosis of ALS can be challenging, as it usually depends on clinical examination...
The effect of thalidomide on the invasive ability of gastric cancer cells by regulating miR-524-5p/FSTL1.
Cellular and molecular biology (Noisy-le-Grand, France)
Dec 20, 2023
This study aimed to investigate the effect of thalidomide (Thal) regulating microRNA (miR)-524-5p/follistatin-like protein 1 (FSTL1) on the invasion ability of gastric cancer cells. For this purpose, real-time fluorescent quantitative PCR (RT-qPCR) w...
Hessian Regularized -Nonnegative Matrix Factorization and Deep Learning for miRNA-Disease Associations Prediction.
Interdisciplinary sciences, computational life sciences
Dec 15, 2023
Since the identification of microRNAs (miRNAs), empirical research has demonstrated their crucial involvement in the functioning of organisms. Investigating miRNAs significantly bolsters efforts related to averting, diagnosing, and treating intricate...
Improving biosensor accuracy and speed using dynamic signal change and theory-guided deep learning.
Biosensors & bioelectronics
Nov 14, 2023
False results and time delay are longstanding challenges in biosensing. While classification models and deep learning may provide new opportunities for improving biosensor performance, such as measurement confidence and speed, it remains a challenge ...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31037
- Neural Networks, Computer 29719
- Algorithms 26832
- Deep Learning 26346
- Artificial Intelligence 24295
- Robotics 13311
- Image Processing, Computer-Assisted 9521
- Retrospective Studies 9111
- Magnetic Resonance Imaging 6181
- Reproducibility of Results 5592
- Tomography, X-Ray Computed 4771
- Support Vector Machine 4686
- Computational Biology 4237
- Brain 4050
- Computer Simulation 3881
Recent Journals
- Scientific reports 5949
- Sensors (Basel, Switzerland) 4794
- PloS one 4015
- Neural networks : the official journal of the International Neural Network Society 2930
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1859
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1130
- Journal of chemical information and modeling 998
- Nature communications 944
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 861
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 826