AIMC Topic: Microscopy

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Deep learning method for malaria parasite evaluation from microscopic blood smear.

Artificial intelligence in medicine
OBJECTIVE: Malaria remains a leading cause of global morbidity and mortality, responsible for approximately 5,97,000 deaths according to World Malaria Report 2024. The study aims to systematically review current methodologies for automated analysis o...

Digital Cytology Combined With Artificial Intelligence Compared to Conventional Microscopy for Anal Cytology: A Preliminary Study.

Cytopathology : official journal of the British Society for Clinical Cytology
INTRODUCTION: Recent studies have shown that digital cytology (DC) coupled with artificial intelligence (AI) algorithms is a valid approach to the diagnosis of cervico-vaginal lesions using liquid-based cytology (LBC). We evaluated the use of these m...

Recent Advances in Structured Illumination Microscopy: From Fundamental Principles to AI-Enhanced Imaging.

Small methods
Structured illumination microscopy (SIM) has emerged as a pivotal super-resolution technique in biological imaging. This review aims to introduce the fundamental principles of SIM, primarily focuses on the latest developments in super-resolution SIM ...

Data stewardship and curation practices in AI-based genomics and automated microscopy image analysis for high-throughput screening studies: promoting robust and ethical AI applications.

Human genomics
BACKGROUND: Researchers have increasingly adopted AI and next-generation sequencing (NGS), revolutionizing genomics and high-throughput screening (HTS), and transforming our understanding of cellular processes and disease mechanisms. However, these a...

Using Machine Learning and Optical Microscopy Image Analysis of Immunosensors Made on Plasmonic Substrates: Application to Detect the SARS-CoV-2 Virus.

ACS sensors
In this article, we introduce a diagnostic platform comprising an optical microscopy image analysis system coupled with machine learning. Its efficacy is demonstrated in detecting SARS-CoV-2 virus particles at concentrations as low as 1 PFU (plaque-f...

Machine learning with label-free Raman microscopy to investigate ferroptosis in comparison with apoptosis and necroptosis.

Communications biology
Human and animal health rely on balancing cell division and cell death to maintain normal homeostasis. This process is accomplished by regulated cell death (RCD), whose imbalance can lead to disease. Currently, the most frequently used method for ana...

ResGloTBNet: An interpretable deep residual network with global long-range dependency for tuberculosis screening of sputum smear microscopy images.

Medical engineering & physics
Tuberculosis is a high-mortality infectious disease. Manual sputum smear microscopy is a common and effective method for screening tuberculosis. However, it is time-consuming, labor-intensive, and has low sensitivity. In this study, we propose ResGlo...

Machine learning models for segmentation and classification of cyanobacterial cells.

Photosynthesis research
Timelapse microscopy has recently been employed to study the metabolism and physiology of cyanobacteria at the single-cell level. However, the identification of individual cells in brightfield images remains a significant challenge. Traditional inten...

Accelerating biopharmaceutical cell line selection with label-free multimodal nonlinear optical microscopy and machine learning.

Communications biology
The selection of high-performing cell lines is crucial for biopharmaceutical production but is often time-consuming and labor-intensive. We investigated label-free multimodal nonlinear optical microscopy for non-perturbative profiling of biopharmaceu...

Detecting living microalgae in ship ballast water based on stained microscopic images and deep learning.

Marine pollution bulletin
Motivated by the need of rapid detection of living microalgae cells in ship ballast water, this study is intended to determine the activities of microalgae using stained microscopic images and detect the living cells with image processing algorithms....