AIMC Topic: Microtubules

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Novel approaches for glioblastoma treatment: Focus on tumor heterogeneity, treatment resistance, and computational tools.

Cancer reports (Hoboken, N.J.) Nov 11, 2019
BACKGROUND: Glioblastoma (GBM) is a highly aggressive primary brain tumor. Currently, the suggested line of action is the surgical resection followed by radiotherapy and treatment with the adjuvant temozolomide, a DNA alkylating agent. However, the a...
Tumor Suppressor Protein p53 Tumor Suppressor Proteins Drug Resistance, Neoplasm Microtubules Antineoplastic Combined Chemotherapy Protocols Prognosis DNA Mutational Analysis Glioblastoma Tumor Microenvironment DNA Repair Enzymes Cancer Vaccines Immune Checkpoint Inhibitors Models, Genetic Mutation Computational Biology Chemoradiotherapy, Adjuvant Genetic Heterogeneity Brain Neoplasms Humans Brain Clonal Evolution Machine Learning Precision Medicine DNA Modification Methylases
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AMC-Net: Asymmetric and multi-scale convolutional neural network for multi-label HPA classification.

Computer methods and programs in biomedicine Jul 9, 2019
BACKGROUND AND OBJECTIVES: The multi-label Human Protein Atlas (HPA) classification can yield a better understanding of human diseases and help doctors to enhance the automatic analysis of biomedical images. The existing automatic protein recognition...
Algorithms Phenotype Reproducibility of Results Humans Neural Networks, Computer False Positive Reactions Microscopy Probability Databases, Protein Microtubules Image Processing, Computer-Assisted Pattern Recognition, Automated Microscopy, Fluorescence Proteins Cell Nucleus
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3D Visualization of Microtubules in Epidermal Pavement Cells.

Methods in molecular biology (Clifton, N.J.) Jan 1, 2023
The plant cytoskeleton is instrumental in cellular processes such as cell growth, differentiation, and immune response. Microtubules, in particular, play a crucial role in morphogenesis by governing the deposition of plant cell wall polysaccharides a...
Microtubules Cytoskeleton Arabidopsis Artificial Intelligence Imaging, Three-Dimensional
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Construction of Molecular Robots from Microtubules for Programmable Swarming.

Methods in molecular biology (Clifton, N.J.) Jan 1, 2022
Swarm robotics has been attracting much attention in recent years in the field of robotics. This chapter describes a methodology for the construction of molecular swarm robots through precise control of active self-assembly of microtubules (MTs). Det...
DNA Microtubules Computers, Molecular Robotics
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Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.

Advances in experimental medicine and biology Jan 1, 2016
Here we propose a model of a peripheral axon with a great deal of autonomy from its cell body-the autonomous axon-but with a substantial dependence on its ensheathing Schwann cell (SC), the axon-SC unit. We review evidence in several fields and show ...
Schwann Cells Sural Nerve Nerve Regeneration Ribosomes Biological Transport Exosomes Axons Signal Transduction Microtubules Humans Action Potentials Cell Communication Phenotype RNA, Messenger Animals Rats Neural Networks, Computer
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A self-powered kinesin-microtubule system for smart cargo delivery.

Nanoscale Jan 7, 2015
A smart self-powered cargo delivery system that is composed of creatine phosphate kinase (CPK) microspheres, kinesins and microtubules is demonstrated. The CPK microsphere not only acts as an ATP generation and buffering system, but also as a carrier...
Kinesins Microtubules Robotics Particle Size Delayed-Action Preparations Materials Testing Molecular Motor Proteins Nanocapsules Motion
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