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Unsupervised machine learning approach to interpret complex lower urinary tract symptoms and their impact on quality of life in adult women.
World journal of urology
Aug 4, 2025
PURPOSE: To identify clinically meaningful clusters of lower urinary tract symptoms (LUTS) in adult women using an unsupervised machine learning approach and to examine their associations with patient-centered outcomes, including quality of life (QoL...
Combined nomogram for differentiating adrenal pheochromocytoma from large-diameter lipid-poor adenoma using multiphase CT radiomics and clinico-radiological features.
BMC medical imaging
Aug 4, 2025
BACKGROUND AND OBJECTIVE: Adrenal incidentalomas (AIs) are predominantly adrenal adenomas (80%), with a smaller proportion (7%) being pheochromocytomas(PHEO). Adenomas are typically non-functional tumors managed through observation or medication, wit...
Early prediction of proton therapy dose distributions and DVHs for hepatocellular carcinoma using contour-based CNN models from diagnostic CT and MRI.
Radiation oncology (London, England)
Aug 4, 2025
BACKGROUND: Proton therapy is commonly used for treating hepatocellular carcinoma (HCC); however, its feasibility can be challenging to assess in large tumors or those adjacent to critical organs at risk (OARs), which are typically assessed only afte...
Facilitators and barriers for using artificial intelligence in cancer pain assessment: a qualitative study.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Aug 4, 2025
OBJECTIVES: This study qualitatively explored healthcare providers' perception regarding the use of modern technology, specifically artificial intelligence (AI), in the assessment and management of cancer pain. It also aimed to identify barriers to a...
A multimodal dataset for precision oncology in head and neck cancer.
Nature communications
Aug 4, 2025
Head and neck cancer is a common disease and is associated with a poor prognosis. A promising approach to improving patient outcomes is personalized treatment, which uses information from a variety of modalities. However, only little progress has bee...
Classification of patients with relapsed/refractory large B-cell lymphoma who do not develop early CRS/NE toxicity using ZUMA clinical trial data.
Journal for immunotherapy of cancer
Aug 4, 2025
BACKGROUND: We aimed to develop an actionable and feasible prospective clinical model to estimate toxicity risk to assist chimeric antigen receptor (CAR) T-cell therapy providers with the management of patients with relapsed and/or refractory large B...
Exhaled gas biomarkers: a non-invasive approach for distinguishing diabetes and its complications.
The Analyst
Aug 4, 2025
Exhaled gas detection offers a safe, convenient, and non-invasive clinical diagnostic method for preventing the progression of diabetes to complications. In this study, gas chromatography-mass spectrometry (GC-MS) analysis and statistical methods wer...
Machine learning and SHAP value interpretation for predicting the response to neoadjuvant chemotherapy and long-term clinical outcomes in Chinese female breast cancer.
Annals of medicine
Aug 3, 2025
BACKGROUND: Most models of neoadjuvant chemotherapy (NACT) for breast cancer (BC) suffer from insufficient data and lack interpretability. Additionally, there is a notable absence of reports from China in this field. This study is also the first to i...
Association between air pollution and type II diabetes in Italy from clinical data and population-weighted exposure at the municipality level.
Scientific reports
Aug 3, 2025
A growing body of literature supports the association between ambient particulate pollution and the risk of type 2 diabetes (T2DM). Both issues are particularly relevant in Italy. This study investigates the relationship between T2DM and exposure to ...
The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria.
Acta dermato-venereologica
Aug 3, 2025
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predic...
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