AIMC Topic: Middle Aged

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Attention-based multimodal deep learning for interpretable and generalizable prediction of pathological complete response in breast cancer.

Journal of translational medicine
BACKGROUND: Accurate prediction of pathological complete response (pCR) to neoadjuvant chemotherapy has significant clinical utility in the management of breast cancer treatment. Although multimodal deep learning models have shown promise for predict...

Predicting antiretroviral therapy adherence status of adult HIV-positive patients using machine-learning Northwest, Ethiopia, 2025.

BMC medical informatics and decision making
BACKGROUND: Adherence with Anti-Retroviral Therapy (ART) reduces viral load, as well as HIV-related morbidity and mortality. Despite the expanded availability of ART, non-adherence remains a series problem, leads increased viral load, a decline CD4 c...

Interpretive prediction of hyperuricemia and gout patients via machine learning analysis of human gut microbiome.

BMC microbiology
Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data f...

Machine learning models predict risk of lower extremity deep vein thrombosis in hospitalized patients with spontaneous intracerebral hemorrhage.

Scientific reports
Lower extremity deep vein thrombosis is one of the important complications of spontaneous intracerebral hemorrhage. We aimed to develop a risk assessment model to predict the risk of lower extremity DVT during hospitalization in patients with spontan...

Inflammatory, fibrotic and endothelial biomarker profiles in COVID-19 patients during and following hospitalization.

Scientific reports
Survivors of severe COVID-19 often suffer from long-term respiratory issues, but the molecular drivers of this damage remain unclear. This study explored the dynamics of inflammatory, fibrotic, and endothelial biomarkers in hospitalized COVID-19 pati...

Exploration and validation of the prognostic value of mitophagy and mitochondrial dynamics-related genes in cervical cancer.

Scientific reports
The mechanisms underlying mitophagy and mitochondrial dynamics (MD) in cervical cancer (CC), a disease with a high mortality rate, remain poorly understood. This study aimed to assess the prognostic significance of these processes in CC. Mendelian ra...

AI Predictive Model of Mortality and Intensive Care Unit Admission in the COVID-19 Pandemic: Retrospective Population Cohort Study of 12,000 Patients.

Journal of medical Internet research
BACKGROUND: One of the main challenges with COVID-19 has been that although there are known factors associated with a worse prognosis, clinicians have been unable to predict which patients, with similar risk factors, will die or require intensive car...

Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes.

Neurosurgical review
Accurately predicting the severity of subarachnoid hemorrhage (SAH) is critical for informing clinical decisions and improving patient outcomes. This study addresses the challenges of imbalanced data in SAH severity classification by employing the Mo...