Translational research : the journal of laboratory and clinical medicine
Jul 1, 2025
Acute Respiratory Distress Syndrome (ARDS), characterized by the rapid onset of respiratory failure and mortality rates of ∼40%, remains a significant challenge in critical care medicine. Despite advances in supportive care, accurate prediction of AR...
This review paper comprehensively examines recent advancements in machine learning (ML) applications within biofluid mechanics, with a targeted focus on enabling clinically actionable diagnostics and simulations. It demonstrates how ML, and in partic...
In the paper we presented the review of mathematical and numerical models of osteoarthritis (OA). As angiogenesis seems to be the most principal factor in OA mathematical and numerical modelling, we focused on the models that consider the process. Th...
Breast reconstruction using tissue expanders is the primary treatment option following mastectomy. Although skin growth in response to chronic supra-physiological stretch is well-established, individual patient factors such as breast shape, volume, s...
Six-degree-of-freedom robotic testing is used to gain insight into knee function by measuring the biomechanics of cadaveric knees. However, it can be challenging to use cadaveric knees to validate robotic testing methodologies and to compare methodol...
Journal of the mechanical behavior of biomedical materials
Jul 1, 2025
Understanding the complexities of single-cell migration is facilitated by computational modeling, which provides important insights into the physiological processes that underlie migration mechanisms. This study developed a computational model for on...
Virtual cells are an emerging frontier at the intersection of artificial intelligence and biology. A key goal of these cell state models is predicting cellular responses to perturbations. The Virtual Cell Challenge is being established to catalyze pr...
Journal of pharmacokinetics and pharmacodynamics
Jun 16, 2025
Quantitative Systems Pharmacology (QSP) has emerged as a cornerstone of modern drug development, providing a robust framework to integrate data from preclinical and clinical studies, enhance decision-making, and optimize therapeutic strategies. By mo...
. Accurately and in real-time simulating soft tissue deformation and visualizing stress distribution are crucial for advancing surgical simulators closer to real surgical environments. The concept of using neural networks to accelerate the finite ele...
International journal of pharmaceutics
Jun 10, 2025
Chronic obstructive pulmonary disease (COPD) plays a heavy burden on individuals and the social health system, not only causing direct medical costs but also economic losses. Today, treatments for COPD include drugs, bronchodilators, and oxygen thera...
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