The erratic nature of cardiac rhythms can precipitate a multitude of pathologies. Consequently, the endeavor to achieve stabilization of the human heartbeat has garnered significant scholarly interest in recent years. In this context, an adaptive non...
Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and time-consumi...
Coronary artery disease (CAD) remains the leading cause of mortality, creating an urgent need for reproducible, image-based decision support. Although YOLOv8-based detectors underpin much of today's state-of-the-art stenosis detection, their accuracy...
INTRODUCTION: Heart Disease (HD) stands as the foremost reason for mortality all over the world for both men and women. Millions of people are affected worldwide every year, resulting in numerous fatalities. Timely and precise detection is essential ...
Computer methods and programs in biomedicine
Jun 23, 2025
BACKGROUND AND OBJECTIVE: Population-scale hemodynamic research faces limitations due to the trade-off between computationally expensive patient-specific Computational Fluid Dynamics (CFD) and overly idealized cylindrical models. To overcome this, we...
Cardiovascular diseases remain a major cause of mortality and disability, underscoring the need for improved analysis of brain hemodynamics. The Circle of Willis plays a crucial role in maintaining cerebral blood flow; however, conventional measureme...
Coronary artery disease involves the narrowing of coronary vessels due to atherosclerosis and is currently the leading cause of death worldwide. The gold standard for its diagnosis is the fractional flow reserve (FFR) examination, which measures the ...
The International journal of artificial organs
Jun 6, 2025
Ventricular assist devices (VADs) are essential for end-stage heart failure patients, but their design must balance hydraulic efficiency and hemocompatibility to minimize blood damage. This study presents a multi-objective optimization framework inte...
During thrombosis, platelets rapidly deposit and activate on the vessel wall, driving conditions such as myocardial infarction and stroke. The complexity of thrombus formation in pathological flow geometries, along with patient-specific pharmacologic...
A cardiac digital twin is a virtual replica of a patient-specific heart, mimicking its anatomy and physiology. A crucial step of building a cardiac digital twin is anatomical twinning, where the computational mesh of the digital twin is tailored to t...
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