AIMC Topic: Models, Genetic

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Inference and Analysis of Population Structure Using Genetic Data and Network Theory.

Genetics
Clustering individuals to subpopulations based on genetic data has become commonplace in many genetic studies. Inference about population structure is most often done by applying model-based approaches, aided by visualization using distance-based app...

Sparse Inverse Covariance Estimation with L0 Penalty for Network Construction with Omics Data.

Journal of computational biology : a journal of computational molecular cell biology
Constructing coexpression and association networks with omics data is crucial for studying gene-gene interactions and underlying biological mechanisms. In recent years, learning the structure of a Gaussian graphical model from high-dimensional data u...

Neuro-genetic system for optimization of GMI samples sensitivity.

Neural networks : the official journal of the International Neural Network Society
Magnetic sensors are largely used in several engineering areas. Among them, magnetic sensors based on the Giant Magnetoimpedance (GMI) effect are a new family of magnetic sensing devices that have a huge potential for applications involving measureme...

Using Genetic Programming with Prior Formula Knowledge to Solve Symbolic Regression Problem.

Computational intelligence and neuroscience
A researcher can infer mathematical expressions of functions quickly by using his professional knowledge (called Prior Knowledge). But the results he finds may be biased and restricted to his research field due to limitation of his knowledge. In cont...

SVM2Motif--Reconstructing Overlapping DNA Sequence Motifs by Mimicking an SVM Predictor.

PloS one
Identifying discriminative motifs underlying the functionality and evolution of organisms is a major challenge in computational biology. Machine learning approaches such as support vector machines (SVMs) achieve state-of-the-art performances in genom...

Evolutionary multiobjective design of a flexible caudal fin for robotic fish.

Bioinspiration & biomimetics
Robotic fish accomplish swimming by deforming their bodies or other fin-like appendages. As an emerging class of embedded computing system, robotic fish are anticipated to play an important role in environmental monitoring, inspection of underwater s...

The transfer and transformation of collective network information in gene-matched networks.

Scientific reports
Networks, such as the human society network, social and professional networks, and biological system networks, contain vast amounts of information. Information signals in networks are distributed over nodes and transmitted through intricately wired l...

Prioritizing Clinically Relevant Copy Number Variation from Genetic Interactions and Gene Function Data.

PloS one
It is becoming increasingly necessary to develop computerized methods for identifying the few disease-causing variants from hundreds discovered in each individual patient. This problem is especially relevant for Copy Number Variants (CNVs), which can...

Genetic Learning Particle Swarm Optimization.

IEEE transactions on cybernetics
Social learning in particle swarm optimization (PSO) helps collective efficiency, whereas individual reproduction in genetic algorithm (GA) facilitates global effectiveness. This observation recently leads to hybridizing PSO with GA for performance e...

Genome instability model of metastatic neuroblastoma tumorigenesis by a dictionary learning algorithm.

BMC medical genomics
BACKGROUND: Metastatic neuroblastoma (NB) occurs in pediatric patients as stage 4S or stage 4 and it is characterized by heterogeneous clinical behavior associated with diverse genotypes. Tumors of stage 4 contain several structural copy number aberr...