AIMC Topic: Models, Statistical

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LEAP: Using machine learning to support variant classification in a clinical setting.

Human mutation
Advances in genome sequencing have led to a tremendous increase in the discovery of novel missense variants, but evidence for determining clinical significance can be limited or conflicting. Here, we present Learning from Evidence to Assess Pathogeni...

Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury.

Journal of clinical epidemiology
OBJECTIVE: We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury.

Human respiration monitoring using infrared thermography and artificial intelligence.

Biomedical physics & engineering express
The respiration rate (RR) is the most vital parameter used for the determination of human health. The most widely adopted techniques, used to monitor the RR are contact in nature and face many drawbacks. This paper reports the use of Infrared Thermog...

A knowledge-driven feature learning and integration method for breast cancer diagnosis on multi-sequence MRI.

Magnetic resonance imaging
BACKGROUND: The classification of benign versus malignant breast lesions on multi-sequence Magnetic Resonance Imaging (MRI) is a challenging task since breast lesions are heterogeneous and complex. Recently, deep learning methods have been used for b...

Probabilistic inference of binary Markov random fields in spiking neural networks through mean-field approximation.

Neural networks : the official journal of the International Neural Network Society
Recent studies have suggested that the cognitive process of the human brain is realized as probabilistic inference and can be further modeled by probabilistic graphical models like Markov random fields. Nevertheless, it remains unclear how probabilis...

Automated prediction of mastitis infection patterns in dairy herds using machine learning.

Scientific reports
Mastitis in dairy cattle is extremely costly both in economic and welfare terms and is one of the most significant drivers of antimicrobial usage in dairy cattle. A critical step in the prevention of mastitis is the diagnosis of the predominant route...

One model to rule them all? Using machine learning algorithms to determine the number of factors in exploratory factor analysis.

Psychological methods
Determining the number of factors is one of the most crucial decisions a researcher has to face when conducting an exploratory factor analysis. As no common factor retention criterion can be seen as generally superior, a new approach is proposed-comb...

Predicting Wait Times in Pediatric Ophthalmology Outpatient Clinic Using Machine Learning.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Patient perceptions of wait time during outpatient office visits can affect patient satisfaction. Providing accurate information about wait times could improve patients' satisfaction by reducing uncertainty. However, these are rarely known about effi...

Comparison of Prediction Model Performance Updating Protocols: Using a Data-Driven Testing Procedure to Guide Updating.

AMIA ... Annual Symposium proceedings. AMIA Symposium
In evolving clinical environments, the accuracy of prediction models deteriorates over time. Guidance on the design of model updating policies is limited, and there is limited exploration of the impact of different policies on future model performanc...

Interpretation of machine learning predictions for patient outcomes in electronic health records.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Electronic health records are an increasingly important resource for understanding the interactions between patient health, environment, and clinical decisions. In this paper we report an empirical study of predictive modeling of seven patient outcom...