Clinical lymphoma, myeloma & leukemia
Dec 21, 2015
INTRODUCTION: The present study evaluated the pharmacokinetics and safety of elotuzumab, a humanized IgG1 monoclonal antibody against signaling lymphocyte activation molecule-F7, combined with lenalidomide and dexamethasone, in patients with multiple...
BACKGROUND: Multiple myeloma (MM) is a hematological malignancy that progresses from a benign precursor stage known as Monoclonal Gammopathy of Undetermined Significance (MGUS). Distinguishing MM from MGUS at the molecular level by identifying key bi...
OBJECTIVES: Optimize deep learning-based vertebrae segmentation in longitudinal CT scans of multiple myeloma patients using structural uncertainty analysis.
Purpose To construct and evaluate the performance of a machine learning model for bone segmentation using whole-body CT images. Materials and Methods In this retrospective study, whole-body CT scans (from June 2010 to January 2018) from 90 patients (...
Venous thromboembolic events (VTE) is a frequent complication in multiple myeloma (MM) patients, raising mortality. This study aims to use machine learning to identify VTE risk factors in MM, helping to pinpoint high-risk individuals for better clini...
PURPOSE: Stage in multiple myeloma (MM) is an essential measure of disease risk, but its measurement in large databases is often lacking. We aimed to develop and validate a natural language processing (NLP) algorithm to extract oncologists' documenta...
UNLABELLED: Bone marrow trephine biopsy is crucial for the diagnosis of multiple myeloma. However, the complexity of bone marrow cellular, morphologic, and spatial architecture preserved in trephine samples hinders comprehensive evaluation. To dissec...
Medical archives (Sarajevo, Bosnia and Herzegovina)
Dec 1, 2016
INTRODUCTION: Anemia occurs in 60% to 80 % of patients with newly diagnosed myeloma multiplex (MM). The cause of anemia in MM is probably multi factorial and involved among the others hepcidin and some cytokines, especially interleukine-6. Anemia in ...
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