Clinical heterogeneity among hemodialysis patients necessitates precision medicine approaches transcending conventional single-parameter management. Through machine learning analysis of 1,207 maintenance hemodialysis patients, we developed a novel tw...
Chemical communications (Cambridge, England)
Aug 28, 2025
There is a growing interest in developing one-health "plug and play" platforms for making different therapeutics/prophylactics to target various biological entities such as viruses, cancer cells, or bacteria. Such a platform could benefit from advanc...
Ferritin is an iron-storage protein that naturally self-assembles into a hollow spherical particle consisting of 24 identical subunits, and it serves a central role in iron metabolism. Ferritin's favorable drug-loading capacity, biocompatibility, int...
OBJECTIVE: While ferritinophagy is believed to play a significant role in the development of periodontitis, the exact mechanisms remain unclear. This study aimed to investigate the biomarkers associated with ferritinophagy in periodontitis using tran...
INTRODUCTION: Triple-negative breast cancer (TNBC) is the primary cause of breast cancer-induced death in women. Literature has confirmed the benefits of Salidroside (Sal) in treating TNBC. However, the study about potential therapeutic targets and m...
Anais da Academia Brasileira de Ciencias
Jun 24, 2024
The need for the identification of risk factors associated to COVID-19 disease severity remains urgent. Patients' care and resource allocation can be potentially different and are defined based on the current classification of disease severity. This ...
It is important to determine the risk for admission to the intensive care unit (ICU) in patients with COVID-19 presenting at the emergency department. Using artificial neural networks, we propose a new Data Ensemble Refinement Greedy Algorithm (DERGA...
INTRODUCTION: Iron deficiency affects exercise capacity because of the critical role iron plays in the optimal functioning of skeletal muscle metabolism. We hypothesized that intravenous iron may improve exercise tolerance, quality of life (QoL), and...
A novel approach for the synthesis of biosurfactant stabilized/functionalized tungsten disulfide (WS-B) quantum dots (QDs) and its application for ferritin immunosensor is reported. These 2-D layered material derived quantum dots are synthesized via ...
BACKGROUND: Iron food fortification and oral iron formulations are frequently limited by poor absorption, resulting in the widespread use of high-dose oral iron, which is poorly tolerated.
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