AIMC Topic: Nanomedicine

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Optimization of controlled release nanoparticle formulation of verapamil hydrochloride using artificial neural networks with genetic algorithm and response surface methodology.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V May 16, 2015
This study was performed to optimize the formulation of polymer-lipid hybrid nanoparticles (PLN) for the delivery of an ionic water-soluble drug, verapamil hydrochloride (VRP) and to investigate the roles of formulation factors. Modeling and optimiza...
Poloxamer Polysorbates Technology, Pharmaceutical Surface Properties Chemistry, Pharmaceutical Delayed-Action Preparations Calcium Channel Blockers Solubility Nanomedicine Kinetics Verapamil Particle Size Lipids Models, Chemical Polymers Drug Carriers Computer Simulation Nanoparticles Neural Networks, Computer Algorithms
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An Acoustic Communication Technique of Nanorobot Swarms for Nanomedicine Applications.

IEEE transactions on nanobioscience Apr 17, 2015
In this contribution, we present a communication paradigm among nanodevices, based on acoustic vibrations for medical applications. We consider a swarm of nanorobots able to communicate in a distributed and decentralized fashion, propelled in a biolo...
Acoustics Nanomedicine Animal Communication Humans Vibration Robotics Bees Models, Biological Algorithms Animals
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Cellular level robotic surgery: Nanodissection of intermediate filaments in live keratinocytes.

Nanomedicine : nanotechnology, biology, and medicine Sep 6, 2014
We present the nanosurgery on the cytoskeleton of live cells using AFM based nanorobotics to achieve adhesiolysis and mimic the effect of pathophysiological modulation of intercellular adhesion. Nanosurgery successfully severs the intermediate filame...
Surgery, Computer-Assisted Microscopy, Atomic Force Cations Cytoskeleton Autoimmune Diseases Stress, Mechanical Cell Line Cell Adhesion Humans Keratinocytes Intermediate Filaments Robotics Desmosomes Apoptosis Nanostructures Nanomedicine
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Exploring therapeutic and diagnostic potential of cysteine cathepsin as targets for cancer therapy with nanomedicine.

International journal of biological macromolecules Jun 1, 2025
Cysteine cathepsins have been discovered to be substantially expressed in multiple types of cancer. They play a key role in the progression and growth of these cancers, rendering them appealing targets for nanoscale delivery and noninvasive diagnosti...
Drug Delivery Systems Animals Humans Nanomedicine Molecular Targeted Therapy Neoplasms Cathepsins Nanoparticles
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The Role of Machine Learning in Centralized Authorization Process of Nanomedicines in European Union.

Current topics in medicinal chemistry Jan 1, 2021
BACKGROUND: Machine Learning (ML) has experienced an increasing use, given the possibilities to expand the scientific knowledge of different disciplines, such as nanotechnology. This has allowed the creation of Cheminformatic models capable of predic...
European Union Machine Learning Nanomedicine Humans
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Tiny Conveyance: Micro- and Nanorobots Prepare to Advance Medicine.

IEEE pulse Jan 1, 2018
In the science-fiction classic Fantastic Voyage [1], a shrink-ray zaps a submarine and the crew within it, and the resulting microscopic vehicle ventures inside a human body to destroy a blood clot and save a prominent patient's life. While that scen...
Robotics Nanomedicine Humans Bacteria
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Medical microbots need better imaging and control.

Nature May 24, 2017
Humans Robotics Nanomedicine Clinical Trials as Topic Diagnostic Equipment Motion Biocompatible Materials Microchemistry Therapeutics
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