AI Medical Compendium Topic

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Off-Label Use

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Medication-indication knowledge bases: a systematic review and critical appraisal.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Medication-indication information is a key part of the information needed for providing decision support for and promoting appropriate use of medications. However, this information is not readily available to end users, and a lot of the re...

Can Hyperparameter Tuning Improve the Performance of a Super Learner?: A Case Study.

Epidemiology (Cambridge, Mass.)
BACKGROUND: Super learning is an ensemble machine learning approach used increasingly as an alternative to classical prediction techniques. When implementing super learning, however, not tuning the hyperparameters of the algorithms in it may adversel...

Off-Label use of Woven EndoBridge device for intracranial brain aneurysm treatment: Modeling of occlusion outcome.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
INTRODUCTION: The Woven EndoBridge (WEB) device is emerging as a novel therapy for intracranial aneurysms, but its use for off-label indications requires further study. Using machine learning, we aimed to develop predictive models for complete occlus...