Osteoarthritis (OA) is a prevalent condition resulting in physical limitations. Early detection of OA is critical to effectively manage this condition. However, the diagnosis of early-stage arthritis remains challenging. The Kellgren and Lawrence (KL...
OBJECTIVES: To facilitate the stratification of patients with osteoarthritis (OA) for new treatment development and clinical trial recruitment, we created an automated machine learning (autoML) tool predicting the rapid progression of knee OA over a ...
Computer methods and programs in biomedicine
39837061
BACKGROUND AND OBJECTIVES: Accurate prediction of progression in knee osteoarthritis (KOA) is significant for early personalized intervention. Previous methods commonly focused on quantifying features from a specific sub-structure imaged at baseline ...
Knee osteoarthritis (KOA) represents a progressive degenerative disorder characterized by the gradual erosion of articular cartilage. This study aimed to develop and validate biomarker-based predictive models for KOA diagnosis using machine learning ...
Knee arthritis is a prevalent joint condition that affects many people worldwide. Early detection and appropriate treatment are essential to slow the disease's progression and enhance patients' quality of life. In this study, various machine learning...
OBJECTIVES: Primary knee osteoarthritis (KOA) is a heterogeneous disease with clinical and molecular contributors. Biofluids contain microRNAs and metabolites that can be measured by omic technologies. Multimodal deep learning is adept at uncovering ...
Total knee arthroplasty (TKA) is an effective treatment for end stage osteoarthritis. However, biopsychosocial features are not routinely considered in TKA clinical decision-making, despite increasing evidence to support their role in patient recover...
Knee Osteoarthritis (KOA), a leading cause of disability worldwide, is challenging to detect early due to subtle radiographic indicators. Diverse, extensive datasets are needed but are challenging to compile because of privacy, data collection limita...
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
40067469
PURPOSE: Total knee arthroplasty (TKA) is considered the gold standard treatment for end-stage knee osteoarthritis. Common complications associated with TKA include implant loosening and periprosthetic fractures, which often require revision surgery ...
BACKGROUND: Sarcopenia is an age-related progressive skeletal muscle disease that leads to loss of muscle mass and function, resulting in adverse health outcomes such as falls, functional decline, and death. Knee osteoarthritis (KOA) is a common chro...