Nicotinamide mononucleotide (NMN) is a bioactive compound in NAD(P) metabolism, which exhibits diverse pharmaceutical interests. However, enhancing NMN biosynthesis faces the challange of competing with cell growth and disturbing intracellular redox ...
Cytochrome P450 1A2, as many isoenzymes, can generate multiple metabolites from a single substrate. A loose coupling between substrate binding and oxygen activation makes possible substrate reorientations at the active site prior to catalysis. In the...
Food research international (Ottawa, Ont.)
Feb 1, 2025
Current detection methods for lipid and protein oxidation using hyperspectral imaging (HSI) in conjunction with machine learning (ML) necessitate the involvement of data scientists and domain experts to adjust the model architecture and tune hyperpar...
In the process of partial nitrification and anaerobic ammonia oxidation (anammox) for nitrogen removal, the process offers simple metabolic pathways, low operating costs, and high nitrogenous loading rates. However, since the partial nitrification-an...
Machine learning (ML) is expected to bring new insights into the impact of organic structures on the reaction mechanisms in reactive oxygen species oxidation. However, understanding the underlying chemical mechanisms still faces challenges due to the...
Obesity is increasingly taking an important stage as a cause of death worldwide, and interventions with a good cost-effectiveness ratio are needed. is one of these natural products with health benefits. Objective. The present study evaluated the cy...
Two-photon (2P) fluorescence lifetime imaging microscopy (FLIM) was used to track cellular metabolism with drug treatment of auto-fluorescent coenzymes NAD(P)H and FAD in living cancer cells. Simultaneous excitation at 800 nm of both coenzymes was co...
The urgent need to eliminate Perfluorooctanoic Acid (PFOA) has positioned electrooxidation (EO) as a key solution for pollutant degradation. This study evaluates several machine learning (ML) models, including K-Nearest Neighbors (KNN), Decision Tree...
An electrocatalytic platform based on a novel nanocomposite integrated with a grid search-optimized neural network (GSNN) was proposed for intelligent sensing of tryptophan. The cuprospinel-decorated chitosan-functionalized carbon nanofibers (CuFeO/C...
The shelf-life and quality of food products depend heavily on antioxidants, which protect lipids from free radical degradation. α-Tocopherol and myricetin, two potent antioxidants, synergistically enhance the prevention of oxidative rancidity in bulk...
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