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Pancreatic Neoplasms

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Pancreatic Cancer Imaging: A New Look at an Old Problem.

Current problems in diagnostic radiology
Computed tomography is the most commonly used imaging modality to detect and stage pancreatic cancer. Previous advances in pancreatic cancer imaging have focused on optimizing image acquisition parameters and reporting standards. However, current sta...

A machine learning approach identified a diagnostic model for pancreatic cancer through using circulating microRNA signatures.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Late diagnosis of pancreatic cancer (PC) due to the limited effectiveness of modern testing approaches, causes many patients to miss the chance of surgery and consequently leads to a high mortality rate. Pivotal improvements in circulating microRNA e...

Deep learning-based image analysis methods for brightfield-acquired multiplex immunohistochemistry images.

Diagnostic pathology
BACKGROUND: Multiplex immunohistochemistry (mIHC) permits the labeling of six or more distinct cell types within a single histologic tissue section. The classification of each cell type requires detection of the unique colored chromogens localized to...

Radiogenomics for predicting p53 status, PD-L1 expression, and prognosis with machine learning in pancreatic cancer.

British journal of cancer
BACKGROUND: Radiogenomics is an emerging field that integrates "Radiomics" and "Genomics". In the current study, we aimed to predict the genetic information of pancreatic tumours in a simple, inexpensive, and non-invasive manner, using cancer imaging...

Robot-assisted combined pancreatectomy/hepatectomy for metastatic pancreatic acinar cell carcinoma: case report and review of the literature.

Clinical journal of gastroenterology
Acinar cell carcinoma (ACC) of the pancreas is a rare neoplasm with less aggressive behavior than ductal carcinoma. As a result, surgical resection for metastatic ACC is a therapeutic option which can result in long-term survival. There is a paucity ...

Oral microbiome-systemic link studies: perspectives on current limitations and future artificial intelligence-based approaches.

Critical reviews in microbiology
In the past decade, there has been a tremendous increase in studies on the link between oral microbiome and systemic diseases. However, variations in study design and confounding variables across studies often lead to inconsistent observations. In th...

Preliminary clinical application of the robot-assisted CT-guided irreversible electroporation ablation for the treatment of pancreatic head carcinoma.

The international journal of medical robotics + computer assisted surgery : MRCAS
BACKGROUND: To evaluate the feasibility and safety of a robot-guided irreversible electroporation (IRE) ablation system for the treatment of pancreatic head carcinoma.

Network modeling of patients' biomolecular profiles for clinical phenotype/outcome prediction.

Scientific reports
Methods for phenotype and outcome prediction are largely based on inductive supervised models that use selected biomarkers to make predictions, without explicitly considering the functional relationships between individuals. We introduce a novel netw...