AIMC Topic: Pathology, Clinical

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A deep metric learning approach for histopathological image retrieval.

Methods (San Diego, Calif.)
To distinguish ambiguous images during specimen slides viewing, pathologists usually spend lots of time to seek guidance from confirmed similar images or cases, which is inefficient. Therefore, several histopathological image retrieval methods have b...

Novel artificial intelligence system increases the detection of prostate cancer in whole slide images of core needle biopsies.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Prostate cancer (PrCa) is the second most common cancer among men in the United States. The gold standard for detecting PrCa is the examination of prostate needle core biopsies. Diagnosis can be challenging, especially for small, well-differentiated ...

Prognosis in pathology: Are we "prognosticating" or only establishing correlations between independent variables and survival? A study with various analytics cautions about the overinterpretation of statistical results.

Annals of diagnostic pathology
Survival data from 225 patients with resected pulmonary typical carcinoids were analyzed with Kaplan-Meier statistics (K-M) and "deep learning" methods to illustrate the difference between establishing "correlations" and "prognostications". Cases wer...

Automated Detection and Grading of Non-Muscle-Invasive Urothelial Cell Carcinoma of the Bladder.

The American journal of pathology
Accurate grading of non-muscle-invasive urothelial cell carcinoma is of major importance; however, high interobserver variability exists. A fully automated detection and grading network based on deep learning is proposed to enhance reproducibility. A...

Unsupervised Machine Learning in Pathology: The Next Frontier.

Surgical pathology clinics
Applications of artificial intelligence and particularly deep learning to aid pathologists in carrying out laborious and qualitative tasks in histopathologic image analysis have now become ubiquitous. We introduce and illustrate how unsupervised mach...

Artificial intelligence as the next step towards precision pathology.

Journal of internal medicine
Pathology is the cornerstone of cancer care. The need for accuracy in histopathologic diagnosis of cancer is increasing as personalized cancer therapy requires accurate biomarker assessment. The appearance of digital image analysis holds promise to i...

ARA: accurate, reliable and active histopathological image classification framework with Bayesian deep learning.

Scientific reports
Machine learning algorithms hold the promise to effectively automate the analysis of histopathological images that are routinely generated in clinical practice. Any machine learning method used in the clinical diagnostic process has to be extremely a...

Detection of Lung Cancer Lymph Node Metastases from Whole-Slide Histopathologic Images Using a Two-Step Deep Learning Approach.

The American journal of pathology
The application of deep learning for the detection of lymph node metastases on histologic slides has attracted worldwide attention due to its potentially important role in patient treatment and prognosis. Despite this attention, false-positive predic...

Quantifying the effects of data augmentation and stain color normalization in convolutional neural networks for computational pathology.

Medical image analysis
Stain variation is a phenomenon observed when distinct pathology laboratories stain tissue slides that exhibit similar but not identical color appearance. Due to this color shift between laboratories, convolutional neural networks (CNNs) trained with...