We developed an automatic method based on a convolutional neural network (CNN) that identifies metastatic lesions in whole slide images (WSI) of intraoperative frozen sections from sentinel lymph nodes in breast cancer. A total of 954 sentinel lymph ...
The application of deep learning for the detection of lymph node metastases on histologic slides has attracted worldwide attention due to its potentially important role in patient treatment and prognosis. Despite this attention, false-positive predic...
Proceedings of the National Academy of Sciences of the United States of America
Jul 8, 2019
Metastasis of solid tumors is a key determinant of cancer patient survival. Targeting micrometastases using nanoparticles could offer a way to stop metastatic tumor growth before it causes excessive patient morbidity. However, nanoparticle delivery t...
The American journal of surgical pathology
Dec 1, 2018
Advances in the quality of whole-slide images have set the stage for the clinical use of digital images in anatomic pathology. Along with advances in computer image analysis, this raises the possibility for computer-assisted diagnostics in pathology ...
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