AIMC Topic: Phenotype

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The cellular microscopy phenotype ontology.

Journal of biomedical semantics May 18, 2016
BACKGROUND: Phenotypic data derived from high content screening is currently annotated using free-text, thus preventing the integration of independent datasets, including those generated in different biological domains, such as cell lines, mouse and ...
Microscopy Phenotype Biological Ontologies Single-Cell Analysis Cells
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Learning statistical models of phenotypes using noisy labeled training data.

Journal of the American Medical Informatics Association : JAMIA May 12, 2016
OBJECTIVE: Traditionally, patient groups with a phenotype are selected through rule-based definitions whose creation and validation are time-consuming. Machine learning approaches to electronic phenotyping are limited by the paucity of labeled traini...
Myocardial Infarction Vocabulary, Controlled Medical Informatics Computing Logistic Models Models, Statistical Machine Learning Humans Algorithms Phenotype Electronic Health Records Diabetes Mellitus, Type 2
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Extracting a stroke phenotype risk factor from Veteran Health Administration clinical reports: an information content analysis.

Journal of biomedical semantics May 10, 2016
BACKGROUND: In the United States, 795,000 people suffer strokes each year; 10-15 % of these strokes can be attributed to stenosis caused by plaque in the carotid artery, a major stroke phenotype risk factor. Studies comparing treatments for the manag...
Data Mining Veterans Carotid Stenosis Humans Natural Language Processing Government Agencies Algorithms Stroke Phenotype Electronic Health Records Risk Factors
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Machine Learning and Computer Vision System for Phenotype Data Acquisition and Analysis in Plants.

Sensors (Basel, Switzerland) May 5, 2016
Phenomics is a technology-driven approach with promising future to obtain unbiased data of biological systems. Image acquisition is relatively simple. However data handling and analysis are not as developed compared to the sampling capacities. We pre...
Support Vector Machine Artificial Intelligence Bayes Theorem Algorithms Plants Phenotype
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Artificial intelligence in the selection of common bean genotypes with high phenotypic stability.

Genetics and molecular research : GMR Apr 28, 2016
Artificial neural networks have been used for various purposes in plant breeding, including use in the investigation of genotype x environment interactions. The aim of this study was to use artificial neural networks in the selection of common bean g...
Phaseolus Plant Breeding Edible Grain Selection, Genetic Neural Networks, Computer Phenotype Genotype Models, Genetic
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Electronic medical record phenotyping using the anchor and learn framework.

Journal of the American Medical Informatics Association : JAMIA Apr 23, 2016
BACKGROUND: Electronic medical records (EMRs) hold a tremendous amount of information about patients that is relevant to determining the optimal approach to patient care. As medicine becomes increasingly precise, a patient's electronic medical record...
Decision Making, Computer-Assisted Emergency Service, Hospital Databases as Topic Machine Learning Phenotype Humans Electronic Health Records Natural Language Processing Area Under Curve
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MicrO: an ontology of phenotypic and metabolic characters, assays, and culture media found in prokaryotic taxonomic descriptions.

Journal of biomedical semantics Apr 12, 2016
BACKGROUND: MicrO is an ontology of microbiological terms, including prokaryotic qualities and processes, material entities (such as cell components), chemical entities (such as microbiological culture media and medium ingredients), and assays. The o...
Culture Media Biological Ontologies Archaea Phenotype Bacteria
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Simulated herbivory does not constrain phenotypic plasticity to shade through ontogeny in a relict tree.

Plant biology (Stuttgart, Germany) Apr 7, 2016
Ecological limits to phenotypic plasticity (PP), induced by simultaneous biotic and abiotic factors, can prevent organisms from exhibiting optimal plasticity, and in turn lead to decreased fitness. Herbivory is an important biotic stressor and may li...
Phenotype Plant Leaves Light Trees Ecology Seedlings Plant Roots Models, Biological Plant Shoots Herbivory Biological Ontologies Stress, Physiological
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PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability.

Journal of the American Medical Informatics Association : JAMIA Mar 28, 2016
OBJECTIVE: Health care generated data have become an important source for clinical and genomic research. Often, investigators create and iteratively refine phenotype algorithms to achieve high positive predictive values (PPVs) or sensitivity, thereby...
Humans Data Mining Genomics Phenotype International Classification of Diseases Natural Language Processing Algorithms Electronic Health Records Knowledge Bases
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Evaluation of the efficiency of artificial neural networks for genetic value prediction.

Genetics and molecular research : GMR Mar 28, 2016
Artificial neural networks have shown great potential when applied to breeding programs. In this study, we propose the use of artificial neural networks as a viable alternative to conventional prediction methods. We conduct a thorough evaluation of t...
Breeding Selection, Genetic Genetic Fitness Animals Genotype Models, Genetic Neural Networks, Computer Phenotype
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