AIMC Topic: Polyomavirus Infections
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Evaluating Neural Network Performance in Predicting Disease Status and Tissue Source of JC Polyomavirus from Patient Isolates Based on the Hypervariable Region of the Viral Genome.
Viruses
Dec 25, 2024
JC polyomavirus (JCPyV) establishes a persistent, asymptomatic kidney infection in most of the population. However, JCPyV can reactivate in immunocompromised individuals and cause progressive multifocal leukoencephalopathy (PML), a fatal demyelinatin...
Reproducibility and prognostic ability of chronicity parameters in kidney biopsy - Comprehensive evaluation comparing microscopy and artificial intelligence in digital pathology.
Human pathology
Apr 18, 2024
INTRODUCTION: Semi-quantitative scoring of various parameters in renal biopsy is accepted as an important tool to assess disease activity and prognostication. There are concerns on the impact of interobserver variability in its prognostic utility, ge...
Adult
Male
Reproducibility of Results
Aged
Glomerular Filtration Rate
Kidney Diseases
Middle Aged
Kidney
Algorithms
Kidney Transplantation
Prognosis
Female
Humans
Microscopy
Biopsy
Artificial Intelligence
Image Interpretation, Computer-Assisted
Predictive Value of Tests
Observer Variation
Fibrosis
Polyomavirus Infections
Renal Function Impairment in Kidney Transplantation: Importance of Early BK Virus Detection.
Transplantation proceedings
Dec 30, 2018
BACKGROUND: BK virus allograft nephropathy is a major complication of kidney transplantation that markedly reduces graft survival (50% graft failure 24 months after being diagnosed). BK virus replication can occur at any time posttransplantation. Vir...
Urinary exosomal viral microRNA as a marker of BK virus nephropathy in kidney transplant recipients.
PloS one
Dec 21, 2017
OBJECTIVE: Bkv-miR-B1-5p, one of the microRNAs encoded by BK virus, was recently reported to be elevated in the blood among the patients with BK virus nephropathy (BKVN). Urinary exosome was suggested to be a possible source of biomarker for kidney d...
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