International journal of molecular sciences
May 23, 2025
Liquid biopsy has gained attention in oncology as a non-invasive diagnostic tool, offering valuable insights into tumor biology through the analysis of circulating nucleic acid (cfDNA and cfRNA), circulating tumor cells (CTCs), extracellular vesicles...
Advancements in artificial intelligence (AI) are providing a wealth of opportunities for improving clinical practice and healthcare delivery. It is predicted by AI experts that healthcare will change more in the next decade than it has in the previou...
INTRODUCTION: Pancreatic cancer (PC) remains a lethal malignancy with limited treatment options. The role of innate immune cell barrier-related genes in PC prognosis is poorly defined. This study aimed to identify prognostic biomarkers, develop a pre...
International journal of molecular sciences
May 22, 2025
Cardiomyopathies are a heterogeneous group of heart muscle diseases that can lead to heart failure, arrhythmias, and sudden cardiac death. Traditional animal models and in vitro systems have limitations in replicating the complex pathology of human c...
Neoantigens have emerged as ideal targets for personalized cancer immunotherapy. We depict the pan-cancer peptide atlas by comprehensively collecting immunopeptidomics from 531 samples across 14 cancer and 29 normal tissues, and identify 389,165 cano...
International journal of medical informatics
May 18, 2025
INTRODUCTION: Rising healthcare costs and growing demand for personalized preventive care have highlighted the need for data-driven approaches to optimize health check-ups, particularly in corporate settings. This study presents a scoring-based platf...
Breast cancer survival is hard to predict because of the complex ways genes and cells interact. This study offers a new method to improve these predictions by combining gene expression profiling (GEP) with agent-based modeling (ABM). First, GEP will ...
. Personalized transcranial magnetic stimulation (TMS) requires individualized head models that incorporate non-uniform conductivity to enable target-specific stimulation. Accurately estimating non-uniform conductivity in individualized head models r...
Gut microbiota has a crucial role in the pathophysiology of metabolic-associated steatotic liver disease (MASLD), influencing various metabolic mechanisms and contributing to the development of the disease. Dietary interventions targeting gut microbi...
Osteoarthritis (OA) is a complex disorder driven by the combination of environmental and genetic factors. Given its high global prevalence and heterogeneity, developing effective and personalized treatment methods is crucial. This requires identifyin...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.