AIMC Topic: Radiation Dosage

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Physics-driven learning of x-ray skin dose distribution in interventional procedures.

Medical physics
PURPOSE: Radiation doses accumulated during very complicated image-guided x-ray procedures have the potential to cause stochastic, but also deterministic effects, such as skin rashes or even hair loss. To monitor and reduce radiation-related risks to...

The effects of physics-based data augmentation on the generalizability of deep neural networks: Demonstration on nodule false-positive reduction.

Medical physics
PURPOSE: An important challenge for deep learning models is generalizing to new datasets that may be acquired with acquisition protocols different from the training set. It is not always feasible to expand training data to the range encountered in cl...

Gradient regularized convolutional neural networks for low-dose CT image enhancement.

Physics in medicine and biology
The potential risks of x-ray to patients have transferred the public's attention from normal dose CT (NDCT) to low-dose CT (LDCT). However, simply lowering the radiation dose of the CT system will significantly degrade the quality of CT images such a...

A performance comparison of convolutional neural network-based image denoising methods: The effect of loss functions on low-dose CT images.

Medical physics
PURPOSE: Convolutional neural network (CNN)-based image denoising techniques have shown promising results in low-dose CT denoising. However, CNN often introduces blurring in denoised images when trained with a widely used pixel-level loss function. P...

Machine Learning for Automatic Paraspinous Muscle Area and Attenuation Measures on Low-Dose Chest CT Scans.

Academic radiology
RATIONALE AND OBJECTIVES: To develop and evaluate an automated machine learning (ML) algorithm for segmenting the paraspinous muscles on chest computed tomography (CT) scans to evaluate for presence of sarcopenia.

A convolutional neural network for ultra-low-dose CT denoising and emphysema screening.

Medical physics
PURPOSE: Reducing dose level to achieve ALARA is an important task in diagnostic and therapeutic applications of computed tomography (CT) imaging. Effective image quality enhancement strategies are crucial to compensate for the degradation caused by ...

Deep learning-enabled accurate normalization of reconstruction kernel effects on emphysema quantification in low-dose CT.

Physics in medicine and biology
Lung densitometry is being frequently adopted in CT-based emphysema quantification, yet known to be affected by the choice of reconstruction kernel. This study presents a two-step deep learning architecture that enables accurate normalization of reco...

An image-based deep learning framework for individualizing radiotherapy dose.

The Lancet. Digital health
BACKGROUND: Radiotherapy continues to be delivered uniformly without consideration of individual tumor characteristics. To advance toward more precise treatments in radiotherapy, we queried the lung computed tomography (CT)-derived feature space to i...

Estimation of the radiation dose in pregnancy: an automated patient-specific model using convolutional neural networks.

European radiology
OBJECTIVES: The conceptus dose during diagnostic imaging procedures for pregnant patients raises health concerns owing to the high radiosensitivity of the developing embryo/fetus. The aim of this work is to develop a methodology for automated constru...

Ultra-low-dose PET reconstruction using generative adversarial network with feature matching and task-specific perceptual loss.

Medical physics
PURPOSE: Our goal was to use a generative adversarial network (GAN) with feature matching and task-specific perceptual loss to synthesize standard-dose amyloid Positron emission tomography (PET) images of high quality and including accurate pathologi...