International journal of radiation oncology, biology, physics
Nov 13, 2020
PURPOSE: Contouring inconsistencies are known but understudied in clinical radiation therapy trials. We applied auto-contouring to the Radiation Therapy Oncology Group (RTOG) 0617 dose escalation trial data. We hypothesized that the trial heart doses...
International journal of radiation oncology, biology, physics
Nov 13, 2020
PURPOSE: Our purpose was to assess the use of machine learning methods and Mobius 3D (M3D) dose calculation software to reduce the number of physical ion chamber (IC) dose measurements required for patient-specific quality assurance during corona vir...
International journal of radiation oncology, biology, physics
Nov 9, 2020
PURPOSE: This study investigated deep learning models for automatic segmentation to support the development of daily online dose optimization strategies, eliminating the need for internal target volume expansions and thereby reducing toxicity events ...
PURPOSE: To develop and evaluate a volumetric modulated arc therapy (VMAT) machine parameter optimization (MPO) approach based on deep-Q reinforcement learning (RL) capable of finding an optimal machine control policy using previous prostate cancer p...
Range verification in proton therapy is a critical quality assurance task. We studied the feasibility of online range verification based on proton-induced acoustic signals, using a bidirectional long-short-term-memory recurrent neural network and var...
As the main treatment for cancer patients, radiotherapy has achieved enormous advancement over recent decades. However, these achievements have come at the cost of increased treatment plan complexity, necessitating high levels of expertise experience...
PURPOSE: To develop a biological dose prediction model considering tissue bio-reactions in addition to patient anatomy for achieving a more comprehensive evaluation of tumor control and promoting the automatic planning of bulky lung cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Oct 22, 2020
PURPOSE: This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model, via transfer learning with minimal input data, t...
This work aims to develop a voxel-level dose prediction framework by integrating distance information between PTV and OARs, as well as image information, into a densely-connected network (DCNN). Firstly, a four-channel feature map, consisting of a PT...
BACKGROUND: Currently there is an ever increasing interest in Lu-177 targeted radionuclide therapies, which target neuro-endocrine and prostate tumours. For a patient-specific treatment, an individual dosimetry based on SPECT/CT imaging is necessary....