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Radiotherapy Dosage

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Automating the optimization of proton PBS treatment planning for head and neck cancers using policy gradient-based deep reinforcement learning.

Medical physics
BACKGROUND: Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of potentially conflicting planning objectives are involved. Deep reinforcement le...

Deep learning-based Monte Carlo dose prediction for heavy-ion online adaptive radiotherapy and fast quality assurance: A feasibility study.

Medical physics
BACKGROUND: Online adaptive radiotherapy (OART) and rapid quality assurance (QA) are essential for effective heavy ion therapy (HIT). However, there is a shortage of deep learning (DL) models and workflows for predicting Monte Carlo (MC) doses in suc...

Breast radiation therapy fluence painting with multi-agent deep reinforcement learning.

Medical physics
BACKGROUND: The electronic compensation (ECOMP) technique for breast radiation therapy provides excellent dose conformity and homogeneity. However, the manual fluence painting process presents a challenge for efficient clinical operation.

Real-time adaptive proton therapy: An AI-based spatio-temporal mono-energetic dose calculation model (CC-LSTM).

Computers in biology and medicine
PURPOSE: To develop a fully AI-based dose estimation model capable of learning and estimating single pencil beam dose distributions, and to verify its performance by testing the model's generalizability on unseen, previously delivered treatment plans...

Evaluation and failure analysis of four commercial deep learning-based autosegmentation software for abdominal organs at risk.

Journal of applied clinical medical physics
PURPOSE: Deep learning-based segmentation of organs-at-risk (OAR) is emerging to become mainstream in clinical practice because of the superior performance over atlas and model-based autocontouring methods. While several commercial deep learning-base...

A deep learning-based peer review method for radiotherapy planning.

Medical physics
BACKGROUND: Quality control (QC) in radiotherapy planning is crucial for ensuring treatment efficacy and patient safety. Traditionally, QC relies on standard indicators and subjective assessments, which may lead to inconsistencies.

The implementation of knowledge-based planning with partial OAR contours for prostate radiotherapy.

Journal of applied clinical medical physics
PURPOSE: Intra- and inter-observer contour uncertainty is a continuous challenge in treatment planning for radiotherapy. Our proposed solution to address this challenge is the use of partial contours for treatment planning, focusing on uninvolved or ...

Synthetic CT generation from CBCT and MRI using StarGAN in the Pelvic Region.

Radiation oncology (London, England)
RATIONALE AND OBJECTIVES: This study evaluated StarGAN, a deep learning model designed to generate synthetic computed tomography (sCT) images from magnetic resonance imaging (MRI) and cone-beam computed tomography (CBCT) data using a single model. Th...

Multi-task learning for automated contouring and dose prediction in radiotherapy.

Physics in medicine and biology
. Deep learning (DL)-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment pl...

Deep learning-based quick MLC sequencing for MRI-guided online adaptive radiotherapy: a feasibility study for pancreatic cancer patients.

Physics in medicine and biology
One bottleneck of magnetic resonance imaging (MRI)-guided online adaptive radiotherapy is the time-consuming daily online replanning process. The current leaf sequencing method takes up to 10 min, with potential dosimetric degradation and small segme...