AIMC Topic: Rats
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Context-aware deep learning enables high-efficacy localization of high concentration microbubbles for super-resolution ultrasound localization microscopy.
Nature communications
Apr 4, 2024
Ultrasound localization microscopy (ULM) enables deep tissue microvascular imaging by localizing and tracking intravenously injected microbubbles circulating in the bloodstream. However, conventional localization techniques require spatially isolated...
GeneAI 3.0: powerful, novel, generalized hybrid and ensemble deep learning frameworks for miRNA species classification of stationary patterns from nucleotides.
Scientific reports
Mar 26, 2024
Due to the intricate relationship between the small non-coding ribonucleic acid (miRNA) sequences, the classification of miRNA species, namely Human, Gorilla, Rat, and Mouse is challenging. Previous methods are not robust and accurate. In this study,...
Refinement of paramagnetic bead-based digestion protocol for automatic sample preparation using an artificial neural network.
Talanta
Mar 23, 2024
Despite technological advances in the proteomics field, sample preparation still represents the main bottleneck in mass spectrometry (MS) analysis. Bead-based protein aggregation techniques have recently emerged as an efficient, reproducible, and hig...
In Silico Prediction of Oral Acute Rodent Toxicity Using Consensus Machine Learning.
Journal of chemical information and modeling
Mar 18, 2024
Acute oral toxicity (AOT) is required for the classification and labeling of chemicals according to the global harmonized system (GHS). Acute oral toxicity studies are optimized to minimize the use of animals. However, with the advent of the three p...
Enhancing Multi-species Liver Microsomal Stability Prediction through Artificial Intelligence.
Journal of chemical information and modeling
Mar 18, 2024
Liver microsomal stability, a crucial aspect of metabolic stability, significantly impacts practical drug discovery. However, current models for predicting liver microsomal stability are based on limited molecular information from a single species. T...
Time series classification of multi-channel nerve cuff recordings using deep learning.
PloS one
Mar 12, 2024
Neurostimulation and neural recording are crucial to develop neuroprostheses that can restore function to individuals living with disabilities. While neurostimulation has been successfully translated into clinical use for several applications, it rem...
Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques.
Journal of chemical information and modeling
Feb 29, 2024
The world has witnessed a revolution in therapeutics with the development of biological medicines such as antibodies and antibody fragments, notably nanobodies. These nanobodies possess unique characteristics including high specificity and modulatory...
Effect of robotic gait training on muscle and bone characteristics in spinal cord transected rats.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Feb 20, 2024
Osteoporosis and loss of muscle mass are secondary issues with spinal cord injury. Robotic gait training has provided evidence of increasing bone density and muscle mass, but its effect on bone strength is undetermined. The purpose of this study was ...
DeepION: A Deep Learning-Based Low-Dimensional Representation Model of Ion Images for Mass Spectrometry Imaging.
Analytical chemistry
Feb 20, 2024
Mass spectrometry imaging (MSI) is a high-throughput imaging technique capable of the qualitative and quantitative in situ detection of thousands of ions in biological samples. Ion image representation is a technique that produces a low-dimensional v...
Real-Time Tissue Classification Using a Novel Optical Needle Probe for Biopsy.
Applied spectroscopy
Feb 19, 2024
Core needle biopsy is a part of the histopathological process, which is required for cancerous tissue examination. The most common method to guide the needle inside of the body is ultrasound screening, which in greater part is also the only guidance ...
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