AIMC Topic: Rats
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Amplifying the Effects of Contrast Agents on Magnetic Resonance Images Using a Deep Learning Method Trained on Synthetic Data.
Investigative radiology
Jul 28, 2023
OBJECTIVES: Artificial intelligence (AI) methods can be applied to enhance contrast in diagnostic images beyond that attainable with the standard doses of contrast agents (CAs) normally used in the clinic, thus potentially increasing diagnostic power...
A deep-learning assisted bioluminescence tomography method to enable radiation targeting in rat glioblastoma.
Physics in medicine and biology
Jul 24, 2023
. A novel solution is required for accurate 3D bioluminescence tomography (BLT) based glioblastoma (GBM) targeting. The provided solution should be computationally efficient to support real-time treatment planning, thus reducing the x-ray imaging dos...
Bioinspired Soft Spine Enables Small-Scale Robotic Rat to Conquer Challenging Environments.
Soft robotics
Jul 21, 2023
For decades, it has been difficult for small-scale legged robots to conquer challenging environments. To solve this problem, we propose the introduction of a bioinspired soft spine into a small-scale legged robot. By capturing the motion mechanism of...
PMotion: an advanced markerless pose estimation approach based on novel deep learning framework used to reveal neurobehavior.
Journal of neural engineering
Jul 6, 2023
The evaluation of animals' motion behavior has played a vital role in neuromuscular biomedical research and clinical diagnostics, which reflects the changes caused by neuromodulation or neurodamage. Currently, the existing animal pose estimation meth...
Detrimental Effects of Saccharum officinarum Juice on Reproductive Functions of Female Wistar Rats.
Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria
Jun 30, 2023
Changing dietary compositions have contributed to the growing epidemic of metabolic diseases with serious impacts on several aspects of health, including reproductive health. Saccharum officinarum juice has a natural sweetness that makes the general...
Computational prediction of the metabolites of agrochemicals formed in rats.
The Science of the total environment
Jun 22, 2023
Today, computational tools for the prediction of the metabolite structures of xenobiotics are widely available and employed in small-molecule research. Reflecting the availability of measured data, these in silico tools are trained and validated prim...
A feasibility study on AI-controlled closed-loop electrical stimulation implants.
Scientific reports
Jun 22, 2023
Miniaturized electrical stimulation (ES) implants show great promise in practice, but their real-time control by means of biophysical mechanistic algorithms is not feasible due to computational complexity. Here, we study the feasibility of more compu...
Stimulation-mediated reverse engineering of silent neural networks.
Journal of neurophysiology
May 24, 2023
Reconstructing connectivity of neuronal networks from single-cell activity is essential to understanding brain function, but the challenge of deciphering connections from populations of silent neurons has been largely unmet. We demonstrate a protocol...
Prospective Validation of Machine Learning Algorithms for Absorption, Distribution, Metabolism, and Excretion Prediction: An Industrial Perspective.
Journal of chemical information and modeling
May 22, 2023
Absorption, distribution, metabolism, and excretion (ADME), which collectively define the concentration profile of a drug at the site of action, are of critical importance to the success of a drug candidate. Recent advances in machine learning algori...
TransOrGAN: An Artificial Intelligence Mapping of Rat Transcriptomic Profiles between Organs, Ages, and Sexes.
Chemical research in toxicology
May 18, 2023
Animal studies are required for the evaluation of candidate drugs to ensure patient and volunteer safety. Toxicogenomics is often applied in these studies to gain understanding of the underlying mechanisms of toxicity, which is usually focused on cri...
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