European review for medical and pharmacological sciences
Sep 1, 2019
OBJECTIVE: While next generation sequencing (NGS) has become the technology of choice for clinical diagnostics, most genetic laboratories still use Sanger sequencing for orthogonal confirmation of NGS results. Previous studies have shown that when th...
PURPOSE: A substantial portion of medical data is unstructured. Extracting data from unstructured text presents a barrier to advancing clinical research and improving patient care. In addition, ongoing studies have been focused predominately on the E...
PURPOSE: The medical literature relevant to germline genetics is growing exponentially. Clinicians need tools that help to monitor and prioritize the literature to understand the clinical implications of pathogenic genetic variants. We developed and ...
PURPOSE: Drug development in oncology currently is facing a conjunction of an increasing number of antineoplastic agents (ANAs) candidate for phase I clinical trials (P1CTs) and an important attrition rate for final approval. We aimed to develop a ma...
Journal of the National Cancer Institute
Sep 1, 2019
BACKGROUND: Artificial intelligence (AI) systems performing at radiologist-like levels in the evaluation of digital mammography (DM) would improve breast cancer screening accuracy and efficiency. We aimed to compare the stand-alone performance of an ...
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Aug 25, 2019
Computer-aided diagnosis based on computed tomography (CT) image can realize the detection and classification of pulmonary nodules, and improve the survival rate of early lung cancer, which has important clinical significance. In recent years, with t...
Studies in health technology and informatics
Aug 21, 2019
OBJECTIVE: To characterize the scientific reproducibility of biomedical research studies by query and analysis of semantic provenance graphs generated from provenance metadata terms extracted from PubMed articles.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
Aug 15, 2019
STUDY OBJECTIVES: Portable devices for home sleep apnea testing are often limited by their inability to discriminate sleep/wake status, possibly resulting in underestimations. Tracheal sound (TS), which can be visualized as a spectrogram, carries inf...
PURPOSE: Quantifying the risk of cancer associated with pathogenic mutations in germline cancer susceptibility genes-that is, penetrance-enables the personalization of preventive management strategies. Conducting a meta-analysis is the best way to ob...
PURPOSE: The aim of the current study was to assess treatment concordance and adherence to National Comprehensive Cancer Network breast cancer treatment guidelines between oncologists and an artificial intelligence advisory tool.
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