OBJECTIVES: To develop a machine learning-based prediction model using clinical data from the first 24 h of ICU admission to enable rapid screening and early intervention for sepsis patients.
Frontiers in cellular and infection microbiology
Jan 16, 2025
BACKGROUND: Though droplet digital PCR (ddPCR) has emerged as a promising tool for early pathogen detection in bloodstream infections (BSIs), more studies are needed to support its clinical application widely due to different ddPCR platforms with dis...
This research aimed to identify novel indicators for sepsis by analyzing RNA sequencing data from peripheral blood samples obtained from sepsis patients (n = 23) and healthy controls (n = 10). 5148 differentially expressed genes were identified using...
BackgroundIschemic stroke is a critical neurological condition, with infection representing a significant aspect of its clinical management. Sepsis, a life-threatening organ dysfunction resulting from infection, is among the most dangerous complicati...
Frontiers in cellular and infection microbiology
Jan 8, 2025
BACKGROUND: Sepsis is a major cause of mortality in intensive care units (ICUs) and continues to pose a significant global health challenge, with sepsis-related deaths contributing substantially to the overall burden on healthcare systems worldwide. ...
The study aimed to develop and validate a sepsis prediction model using structured electronic medical records (sEMR) and machine learning (ML) methods in emergency triage. The goal was to enhance early sepsis screening by integrating comprehensive tr...
Sepsis, characterized as a systemic inflammatory response triggered by pathogen invasion, represents a continuum that may progress from mild systemic infection to severe sepsis, potentially culminating in septic shock and multiple organ dysfunction s...
International journal of surgery (London, England)
Jan 1, 2025
BACKGROUND: Sepsis remains a significant challenge in patients with major trauma in the ICU. Early detection and treatment are crucial for improving outcomes and reducing mortality rates. Nonetheless, clinical tools for predicting sepsis among patien...
Sepsis-associated encephalopathy (SAE) is common in septic patients, characterized by acute and long-term cognitive impairment, and is associated with higher mortality. This study aimed to identify SAE-related biomarkers and evaluate their diagnostic...
It is evident that Acute Kidney Injury (AKI) is an independent risk factor for both the survival of patients and their kidneys. Here, we present a case of oliguric AKI secondary to blunt trauma-induced crush syndrome complicated with severe sepsis in...
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