Melanoma remains the most aggressive form of skin cancer, characterized by high metastatic potential, genetic heterogeneity, and resistance to conventional therapies. The Melanoma MEGA-Study is a multi-center initiative designed to address these clin...
Studies in health technology and informatics
Aug 7, 2025
This study presents the development and evaluation of an annotation schema and rule-based natural language processing (NLP) system for extracting key melanoma pathology concepts from surgical pathology reports. Achieving high precision and recall, ou...
Nomograms are commonly used in oncology to assist clinicians in individualized decision-making processes, such as considering sentinel node biopsy (SNB) for melanoma patients. Concurrently, artificial intelligence (AI) is increasingly being utilized ...
BACKGROUND: Utilizing automated systems for diagnosing malignant skin lesions promises to improve the early detection of skin diseases and increase patients' survival rates. However, current classification methods primarily focus on global features, ...
Skin cancer encompasses a diverse spectrum of malignancies with increasing global incidence and persistent clinical challenges. Despite advances in therapies such as immune checkpoint inhibitors and targeted agents, many patients-especially those wit...
Deep learning has significantly advanced computer-aided diagnosis, particularly in skin lesion classification. However, achieving high classification performance and providing explainable model predictions remain challenging in medical imaging. To ta...
Computer methods and programs in biomedicine
Jun 1, 2025
BACKGROUND: The clinical diagnosis of skin lesions involves the analysis of dermoscopic and clinical modalities. Dermoscopic images provide detailed views of surface structures, while clinical images offer complementary macroscopic information. Clini...
Cancer biotherapy & radiopharmaceuticals
Jun 1, 2025
This review examined multiple deep learning (DL) methods, including artificial neural networks (ANNs), convolutional neural networks (CNNs), k-nearest neighbors (KNNs), as well as generative adversarial networks (GANs), relying on their abilities to...
Artificial intelligence (AI) systems substantially improve dermatologists' diagnostic accuracy for melanoma, with explainable AI (XAI) systems further enhancing their confidence and trust in AI-driven decisions. Despite these advancements, there rema...
Biosensors are crucial to the diagnosis process since they are designed to detect a specific biological analyte by changing from a biological entity into electrical signals that can be processed for further inspection and analysis. The method provide...
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