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In-Pero: Exploiting Deep Learning Embeddings of Protein Sequences to Predict the Localisation of Peroxisomal Proteins.

International journal of molecular sciences
Peroxisomes are ubiquitous membrane-bound organelles, and aberrant localisation of peroxisomal proteins contributes to the pathogenesis of several disorders. Many computational methods focus on assigning protein sequences to subcellular compartments,...

An Evaluation of the Factors Affecting 'Poacher' Detection with Drones and the Efficacy of Machine-Learning for Detection.

Sensors (Basel, Switzerland)
Drones are being increasingly used in conservation to tackle the illegal poaching of animals. An important aspect of using drones for this purpose is establishing the technological and the environmental factors that increase the chances of success wh...

Development and Application of Medicine-Engineering Integration in the Rehabilitation of Traumatic Brain Injury.

BioMed research international
The rapid progress of the combination of medicine and engineering provides better chances for the clinical treatment and healthcare engineering. Traumatic brain injury (TBI) and its related symptoms have become a major global health problem. At prese...

Dental enumeration and multiple treatment detection on panoramic X-rays using deep learning.

Scientific reports
In this paper, a new powerful deep learning framework, named as DENTECT, is developed in order to instantly detect five different dental treatment approaches and simultaneously number the dentition based on the FDI notation on panoramic X-ray images....

XGBoost based machine learning approach to predict the risk of fall in older adults using gait outcomes.

Scientific reports
This study aimed to identify the optimal features of gait parameters to predict the fall risk level in older adults. The study included 746 older adults (age: 63-89 years). Gait tests (20 m walkway) included speed modification (slower, preferred, and...

DNAscent v2: detecting replication forks in nanopore sequencing data with deep learning.

BMC genomics
BACKGROUND: Measuring DNA replication dynamics with high throughput and single-molecule resolution is critical for understanding both the basic biology behind how cells replicate their DNA and how DNA replication can be used as a therapeutic target f...

MLatom 2: An Integrative Platform for Atomistic Machine Learning.

Topics in current chemistry (Cham)
Atomistic machine learning (AML) simulations are used in chemistry at an ever-increasing pace. A large number of AML models has been developed, but their implementations are scattered among different packages, each with its own conventions for input ...

Robust diagnostic classification via Q-learning.

Scientific reports
Machine learning (ML) models have demonstrated the power of utilizing clinical instruments to provide tools for domain experts in gaining additional insights toward complex clinical diagnoses. In this context these tools desire two additional propert...

AlphaFold - A Personal Perspective on the Impact of Machine Learning.

Journal of molecular biology
I outline how over my career as a protein scientist Machine Learning has impacted my area of science and one of my pastimes, chess, where there are some interesting parallels. In 1968, modelling of three-dimensional structures was initiated based on ...

Recent Applications of Deep Learning Methods on Evolution- and Contact-Based Protein Structure Prediction.

International journal of molecular sciences
The new advances in deep learning methods have influenced many aspects of scientific research, including the study of the protein system. The prediction of proteins' 3D structural components is now heavily dependent on machine learning techniques tha...