International journal of medical informatics
May 22, 2018
BACKGROUND: With the increasing application of electronic health records (EHRs) in the world, protecting private information in clinical text has drawn extensive attention from healthcare providers to researchers. De-identification, the process of id...
Computer methods and programs in biomedicine
May 21, 2018
BACKGROUND AND OBJECTIVES: The refractive index of hemoglobin plays important role in hematology due to its strong correlation with the pathophysiology of different diseases. Measurement of the real part of the refractive index remains a challenge du...
The GO-Cellular Component (GO-CC) ontology provides a controlled vocabulary for the consistent description of the subcellular compartments or macromolecular complexes where proteins may act. Current machine learning-based methods used for the automat...
BACKGROUND: Legacy data and new structured data can be stored in a standardized format as XML-based EHRs on XML databases. Querying documents on these databases is crucial for answering research questions. Instead of using free text searches, that le...
Live-cell microscopy is quickly becoming an indispensable technique for studying the dynamics of cellular processes. Maintaining the specimen in focus during image acquisition is crucial for high-throughput applications, especially for long experimen...
BACKGROUND: Protein dihedral angles provide a detailed description of protein local conformation. Predicted dihedral angles can be used to narrow down the conformational space of the whole polypeptide chain significantly, thus aiding protein tertiary...
With the introduction of various advanced deep learning algorithms, initiatives for image classification systems have transitioned over from traditional machine learning algorithms (e.g., SVM) to Convolutional Neural Networks (CNNs) using deep learni...
In the optimization of deep neural networks (DNNs) via evolutionary algorithms (EAs) and the implementation of the training necessary for the creation of the objective function, there is often a trade-off between efficiency and flexibility. Pure soft...
Cell protrusion is morphodynamically heterogeneous at the subcellular level. However, the mechanism of cell protrusion has been understood based on the ensemble average of actin regulator dynamics. Here, we establish a computational framework called ...
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