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Solid Phase Extraction

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A 6 Second Analytical Method for Quantitation of Tacrolimus in Whole Blood by Use of Laser Diode Thermal Desorption Tandem Mass Spectrometry.

The journal of applied laboratory medicine
BACKGROUND: Therapeutic drug monitoring of immunosuppressive drugs is imperative for organ transplant recipients. High-performance LC-MS/MS is considered gold standard; however, immunoassays provide rapid turnaround time. New technology was developed...

Qualitative and Quantitative Analysis of Cathinones in Human Urine by SPE-GC-MS.

Fa yi xue za zhi
OBJECTIVES: To propose an alternative solid phase extraction-gas chromatography-mass spectrometry (SPE-GC-MS) method for the sensitive determination of cathinones in human urine samples, plus methodological verification.

Derivatization enhances analysis of estrogens and their bioactive metabolites in human plasma by liquid chromatography tandem mass spectrometry.

Analytica chimica acta
Estrogens regulate many diverse biological processes in health and disease. They circulate at a wide range of concentrations in females generating several active metabolites (hydroxy and methoxyestrogens). The metabolites are assumed to be present in...

Magnetic γ-cyclodextrin polymer with compatible cavity promote the magnetic solid-phase extraction of microcystins in water samples.

Analytica chimica acta
Microcystins (MCs), which are produced by eruptive cyanobacteria, seriously threaten the health of humans for their poisonousness. Herein, a facile strategy was introduced to synthesize the magnetic γ-cyclodextrin polymer (FeO@PDA@γ-CDP) composite an...

Quantitative analysis of desomorphine in blood and urine using solid phase extraction and gas chromatography-mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Desomorphine, a semi-synthetic opioid, is a component of the street drug Krokodil. Despite continued reports of Krokodil use, confirmation via toxicological testing remains scarce. The lack of confirmed desomorphine reports may be in part due to the ...

Ultra-high-performance liquid chromatography-mass spectrometry method for neutrophil gelatinase-associated lipocalin as a predictive biomarker in acute kidney injury.

Talanta
Neutrophil gelatinase associated lipocalin (NGAL) is a protein that was found to be overexpressed in acute kidney injury (AKI). The rise in NGAL concentration, both in urine or plasma, appears earlier than for other classical renal function markers s...

[Determination of 4 kinds of plant growth regulator in bean sprout by solid phase extraction column coupled with ultra-high performance liquid chromatography].

Wei sheng yan jiu = Journal of hygiene research
OBJECTIVE: A method for the determination of 6-benzylaminopurine( 6-BAP), isopentennyladenine( z-IP), 4-fluorophenoxyacetic acid( 4-FPA), 4-chlorophenoxyacetic acid( 4-CPA) in bean sprout was developed using solid phase extraction column with ultra-h...

[Determination of 3-monochloropropane-1,2-diol in grease food by solid phase extraction-derivatization-gas chromatography-mass spectrometry].

Wei sheng yan jiu = Journal of hygiene research
OBJECTIVE: To establish the method of determination of 3-monochloropropane-1,2-diol( 3-MCPD) in grease food by gas chromatography-mass spectrometry( GC-MS).

Response surface methodology and artificial neural network approach for the optimization of ultrasound-assisted extraction of polyphenols from garlic.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
This paper aimed to establish the optimal conditions for ultrasound-assisted extraction of polyphenols from domestic garlic (Allium sativum L.) using response surface methodology (RSM) and artificial neural network (ANN) approach. A 4-factor-3-level ...

Rapid Assessment of Opioid Exposure and Treatment in Cities Through Robotic Collection and Chemical Analysis of Wastewater.

Journal of medical toxicology : official journal of the American College of Medical Toxicology
INTRODUCTION: Accurate data regarding opioid use, overdose, and treatment is important in guiding community efforts at combating the opioid epidemic. Wastewater-based epidemiology (WBE) is a potential method to quantify community-level trends of opio...