Reproductive biology and endocrinology : RB&E
Nov 27, 2025
BACKGROUND: The application of Artificial Intelligence (AI) to sperm selection during Intracytoplasmic Sperm Injection (ICSI) procedures represents one of the most innovative advances in assisted reproductive technology (ART). Traditional sperm selec...
Cryopreservation of spermatozoa can be used as a cost-effective way of preserving the ever-increasing number of genetically modified mouse lines. Nevertheless, discontinuing the breeding of a line or strain is only warranted after the quality control...
Male infertility affects a significant portion of couples worldwide, with standard semen analysis often failing to identify functional deficiencies in sperm performance. This study presents a microfluidic platform for characterizing sperm flagellar b...
BACKGROUND AND OBJECTIVE: Male fertility assessment through sperm morphology analysis remains a critical component of reproductive health evaluation, as abnormal sperm morphology is strongly correlated with reduced fertility rates and poor assisted r...
Asthenozoospermia and teratozoospermia are common causes of male infertility. Despite their prevalence, the underlying metabolic mechanisms remain poorly understood. In this study, we conducted targeted metabolomic profiling of sperm samples from 131...
Sperm morphology assessment is recognised as a critical, yet variable, test of male fertility. This variability is due in part to the lack of standardised training for morphologists. This study utilised a bespoke 'Sperm Morphology Assessment Standard...
Understanding human fertility requires dynamic and three-dimensional (3D) analysis of sperm movement, which extends beyond the capabilities of traditional datasets focused primarily on two-dimensional sperm motility or static morphological characteri...
The critically endangered kākāpō (Strigops habroptilus) has suffered population declines due to habitat loss, hunting, and predation. Conservation efforts, including translocation to predator-free islands, have helped increase numbers of this flightl...
Biochemical and biophysical research communications
Apr 11, 2025
The inhibition of sperm cAMP and ATP levels, using an FDA-approved medication, may impair sperm motility and, consequently, fertilization, thus paving the way for the development of a male contraceptive. The objective of this study was to define the ...
The oviduct is the site of fertilization and preimplantation embryo development in mammals. Evidence suggests that gametes alter oviductal gene expression. To delineate the adaptive interactions between the oviduct and gamete/embryo, we performed a m...
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