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Deep learning extended depth-of-field microscope for fast and slide-free histology.

Proceedings of the National Academy of Sciences of the United States of America
Microscopic evaluation of resected tissue plays a central role in the surgical management of cancer. Because optical microscopes have a limited depth-of-field (DOF), resected tissue is either frozen or preserved with chemical fixatives, sliced into t...

3D Printed Biomimetic Soft Robot with Multimodal Locomotion and Multifunctionality.

Soft robotics
Soft robots can outperform traditional rigid robots in terms of structural compliance, enhanced safety, and efficient locomotion. However, it is still a grand challenge to design and efficiently manufacture soft robots with multimodal locomotion capa...

Design and testing of a novel gastrointestinal microrobot.

Biomedical microdevices
In order to improve the reliability, safety and whole digestive applicability of the gastrointestinal microrobot (GMR), a novel inchworm-like GMR is proposed in this paper. The expanding mechanism of the robot adopts an overlapping expanding arm stru...

Application of artificial neural networks to predict multiple quality of dry-cured ham based on protein degradation.

Food chemistry
This study investigated protein degradation and quality changes during the processing of dry-cured ham, and then established the multiple quality prediction model based on protein degradation. From the raw material to the curing period, proteolysis i...

Deep-learning-based direct inversion for material decomposition.

Medical physics
PURPOSE: To develop a convolutional neural network (CNN) that can directly estimate material density distribution from multi-energy computed tomography (CT) images without performing conventional material decomposition.

Thrombolysis of Pulmonary Emboli via Endobronchial Ultrasound-Guided Transbronchial Needle Injection.

The Annals of thoracic surgery
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle injection (EBUS-TBNI) is a novel technique for treating peribronchial targets. The aim of this study was to evaluate preliminary feasibility of thrombolysis of pulmonary emboli via EBU...

Comparative Analysis of Cutting Forces, Torques, and Vibration in Drilling of Bovine, Porcine, and Artificial Femur Bone with Considerations for Robot Effector Stiffness.

Journal of healthcare engineering
Bone drilling is known as one of the most sensitive milling processes in biomedical engineering field. Fracture behavior of this cortical bone during drilling has attracted the attention of many researchers; however, there are still impending concern...

Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.

PLoS computational biology
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's conditions would provide va...

Machine Learning-Assisted Raman Spectroscopy for pH and Lactate Sensing in Body Fluids.

Analytical chemistry
This study presents the combination of Raman spectroscopy with machine learning algorithms as a prospective diagnostic tool capable of detecting and monitoring relevant variations of pH and lactate as recognized biomarkers of several pathologies. The...

A novel fluoroscopy-based robot system for pedicle screw fixation surgery.

The international journal of medical robotics + computer assisted surgery : MRCAS
BACKGROUND: Robot-assisted pedicle screw insertion has gained popularity in the spinal surgery field. Due to high cost, these spinal robots are not extensively applied in clinical surgeries. Developing an effective robot system with low cost and high...