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Synaptic Transmission

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Modulation of the dynamics of cerebellar Purkinje cells through the interaction of excitatory and inhibitory feedforward pathways.

PLoS computational biology
The dynamics of cerebellar neuronal networks is controlled by the underlying building blocks of neurons and synapses between them. For which, the computation of Purkinje cells (PCs), the only output cells of the cerebellar cortex, is implemented thro...

Controllable high-performance memristors based on 2D FeGeTeoxide for biological synapse imitation.

Nanotechnology
Memristors are an important component of the next-generation artificial neural network, high computing systems, etc. In the past, two-dimensional materials based memristors have achieved a high performance and low power consumption, though one at the...

Partial information decomposition reveals that synergistic neural integration is greater downstream of recurrent information flow in organotypic cortical cultures.

PLoS computational biology
The directionality of network information flow dictates how networks process information. A central component of information processing in both biological and artificial neural networks is their ability to perform synergistic integration-a type of co...

Characterization of multiscale logic operations in the neural circuits.

Frontiers in bioscience (Landmark edition)
: Ever since the seminal work by McCulloch and Pitts, the theory of neural computation and its philosophical foundation known as 'computationalism' have been central to brain-inspired artificial intelligence (AI) technologies. The present study descr...

A novel machine learning-based approach for the detection and analysis of spontaneous synaptic currents.

PloS one
Spontaneous synaptic activity is a hallmark of biological neural networks. A thorough description of these synaptic signals is essential for understanding neurotransmitter release and the generation of a postsynaptic response. However, the complexity...

Neural Information Processing and Computations of Two-Input Synapses.

Neural computation
Information processing in artificial neural networks is largely dependent on the nature of neuron models. While commonly used models are designed for linear integration of synaptic inputs, accumulating experimental evidence suggests that biological n...

Spiking Neural Membrane Systems with Adaptive Synaptic Time Delay.

International journal of neural systems
Spiking neural membrane systems (or spiking neural P systems, SNP systems) are a new type of computation model which have attracted the attention of plentiful scholars for parallelism, time encoding, interpretability and extensibility. The original S...

Signatures of Bayesian inference emerge from energy-efficient synapses.

eLife
Biological synaptic transmission is unreliable, and this unreliability likely degrades neural circuit performance. While there are biophysical mechanisms that can increase reliability, for instance by increasing vesicle release probability, these mec...

Tipping prediction of a class of large-scale radial-ring neural networks.

Neural networks : the official journal of the International Neural Network Society
Understanding the emergence and evolution of collective dynamics in large-scale neural networks remains a complex challenge. This paper seeks to address this gap by applying dynamical systems theory, with a particular focus on tipping mechanisms. Fir...

A deep learning framework for automated and generalized synaptic event analysis.

eLife
Quantitative information about synaptic transmission is key to our understanding of neural function. Spontaneously occurring synaptic events carry fundamental information about synaptic function and plasticity. However, their stochastic nature and lo...