AIMC Topic: Thyroid Neoplasms

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Can mutation abundance assess the biological behavior of BRAF-positive papillary thyroid carcinoma?

Journal of translational medicine
BACKGROUND: BRAF mutation is the most common genetic change in papillary thyroid carcinoma (PTC). Nevertheless, the association between BRAF mutation status and abundance and the biological behavior of PTC is unclear. Thus, this study investigated wh...

The value of machine learning based on spectral CT quantitative parameters in the distinguishing benign from malignant thyroid micro-nodules.

BMC cancer
BACKGROUND AND AIMS: More cases of thyroid micro-nodules have been diagnosed annually in recent years because of advancements in diagnostic technologies and increased public health awareness. To explore the application value of various machine learni...

Development and validation of a machine learning model for central compartmental lymph node metastasis in solitary papillary thyroid microcarcinoma via ultrasound imaging features and clinical parameters.

BMC medical imaging
BACKGROUND: Papillary thyroid microcarcinoma (PTMC) is the most common malignant subtype of thyroid cancer. Preoperative assessment of the risk of central compartment lymph node metastasis (CCLNM) can provide scientific support for personalized treat...

Fabrication of serum-based SERS-tailored 3D structures for thyroid cancer diagnosis.

Scientific reports
Early detection of thyroid cancer improves patient survival rate from 51.9% to 99.9%. Fine needle aspiration cytology is the primary method for diagnosing thyroid cancer; however, this method is associated with limitations, including diagnostic uncer...

Ultrasound-based classification of follicular thyroid Cancer using deep convolutional neural networks with transfer learning.

Scientific reports
This study aimed to develop and validate convolutional neural network (CNN) models for distinguishing follicular thyroid carcinoma (FTC) from follicular thyroid adenoma (FTA). Additionally, this current study compared the performance of CNN models wi...

A Novel Three-Stage AI-Assisted Approach for Accurate Differential Diagnosis and Classification of NIFTP and Thyroid Neoplasms.

Endocrine pathology
The recent introduction of the term non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) marked a pivotal shift in the classification of encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) lacking ...

Preoperative Identification of Papillary Thyroid Carcinoma Subtypes and Lymph Node Metastasis via Deep Learning-Assisted Surface-Enhanced Raman Spectroscopy.

ACS nano
Accurate preoperative diagnosis of papillary thyroid carcinoma (PTC) histological subtypes and lymph node metastasis is essential for formulating personalized treatment strategies. However, their preoperative diagnosis is challenged by the limited re...

A Deep Learning-Based Artificial Intelligence Model Assisting Thyroid Nodule Diagnosis and Management: Pilot Results for Evaluating Thyroid Malignancy in Pediatric Cohorts.

Thyroid : official journal of the American Thyroid Association
Artificial intelligence (AI) models have shown promise in predicting malignant thyroid nodules in adults; however, research on deep learning (DL) for pediatric cases is limited. We evaluated the applicability of a DL-based model for assessing thyroi...

AI-based multimodal prediction of lymph node metastasis and capsular invasion in cT1N0M0 papillary thyroid carcinoma.

Frontiers in endocrinology
BACKGROUND: Accurate preoperative evaluation of cT1N0M0 papillary thyroid carcinoma (PTC) is essential for guiding appropriate treatment strategies. Although ultrasound is widely used for clinical staging, it has limitations in detecting lymph node m...

The impact of a simple positioning aid device on the diagnostic performance of thyroid cancer in CT scans: a randomized controlled trial.

Cancer imaging : the official publication of the International Cancer Imaging Society
OBJECTIVE: To evaluate the effectiveness of a simple positioning aid device in neck CT scans for the diagnosis of thyroid cancer, with a focus on its influence on image quality and diagnostic accuracy.