AIMC Topic: Uncertainty

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Explainable Graph Neural Networks in Chemistry: Combining Attribution and Uncertainty Quantification.

Journal of chemical information and modeling
Graph Neural Networks (GNNs) are powerful tools for predicting chemical properties, but their black-box nature can limit trust and utility. Explainability through feature attribution and awareness of prediction uncertainty are critical for practical ...

Uncertainty aware domain incremental learning for cross domain depression detection.

Scientific reports
Deep learning techniques have demonstrated significant promise for detecting Major Depressive Disorder (MDD) from textual data but they still face limitations in real-world scenarios. Specifically, given the limited data availability, some efforts ha...

Leveraging machine learning predicted confidence for boosting assay submission and decision-making efficiencies.

European journal of medicinal chemistry
Machine learning (ML) has become very popular, and its benefits are widely recognized within the scientific community. The ability of ML approaches to leverage large datasets to find patterns among composite single data points has made these approach...

Uncertainty-based cardiac image registration using variational autoencoder with nonuniformly spaced control points.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: The Variational Bayesian (VB) image registration model has garnered recent attention for its ability to offer uncertainty, particularly in the context of cardiac motion estimation. Nonetheless, several challenges have plague...

Towards more reliable prostate cancer detection: Incorporating clinical data and uncertainty in MRI deep learning.

Computers in biology and medicine
Prostate cancer (PCa) is one of the most common cancers among men, and artificial intelligence (AI) is emerging as a promising tool to enhance its diagnosis. This work proposes a classification approach for PCa cases using deep learning techniques. W...

Aggregating soft labels from crowd annotations improves uncertainty estimation under distribution shift.

PloS one
Selecting an effective training signal for machine learning tasks is difficult: expert annotations are expensive, and crowd-sourced annotations may not be reliable. Recent work has demonstrated that learning from a distribution over labels acquired f...

Simulating workload reduction with an AI-based prostate cancer detection pathway using a prediction uncertainty metric.

European radiology
OBJECTIVES: This study compared two uncertainty quantification (UQ) metrics to rule out prostate MRI scans with a high-confidence artificial intelligence (AI) prediction and investigated the resulting potential radiologist's workload reduction in a c...

SASWISE-UE: Segmentation and synthesis with interpretable scalable ensembles for uncertainty estimation.

Computers in biology and medicine
This paper introduces an efficient sub-model ensemble framework aimed at enhancing the interpretability of medical deep learning models, thus increasing their clinical applicability. By generating uncertainty maps, this framework enables end-users to...

Uncertainty Quantification and Temperature Scaling Calibration for Protein-RNA Binding Site Prediction.

Journal of chemical information and modeling
The black-box nature of deep learning has increasingly drawn attention to the reliability and uncertainty of predictive models. Currently, several uncertainty quantification (UQ) methods have been proposed and successfully applied in the fields of mo...

A controlled trial examining large Language model conformity in psychiatric assessment using the Asch paradigm.

BMC psychiatry
BACKGROUND: Despite significant advances in AI-driven medical diagnostics, the integration of large language models (LLMs) into psychiatric practice presents unique challenges. While LLMs demonstrate high accuracy in controlled settings, their perfor...