AIMC Topic: Uveal Melanoma

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Value of MR-based radiomics in differentiating uveal melanoma from other intraocular masses in adults.

European journal of radiology Sep 8, 2020
PURPOSE: To assess the performance of machine learning (ML)-based magnetic resonance imaging (MRI) radiomics analysis for discriminating between uveal melanoma (UM) and other intraocular masses.
Uveal Neoplasms Uveal Melanoma Diagnosis, Differential Image Enhancement Logistic Models Support Vector Machine Contrast Media Magnetic Resonance Imaging Child ROC Curve Middle Aged Adolescent Humans Eye Neoplasms Aged Young Adult Adult Male Melanoma Reproducibility of Results Retrospective Studies Female
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Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections.

Translational vision science & technology Sep 1, 2020
BACKGROUND: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Monosomy 3 and mutation are strong prognostic factors predicting metastatic risk in UM. Nuclear BAP1 (nBAP1) expression is a close immunohistochemical surro...
Ubiquitin Thiolesterase Uveal Melanoma Hematoxylin Uveal Neoplasms Tumor Suppressor Proteins Eosine Yellowish-(YS) Adult Deep Learning Artificial Intelligence Melanoma Humans
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Gene Expression Profile Prediction in Uveal Melanoma Using Deep Learning: A Pilot Study for the Development of an Alternative Survival Prediction Tool.

Ophthalmology. Retina Jun 18, 2020
Uveal Melanoma Transcriptome Anterior Eye Segment Melanoma Deep Learning Pilot Projects Uveal Neoplasms Biomarkers, Tumor Humans Gene Expression Regulation, Neoplastic
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Machine learning-based integrative analysis of methylome and transcriptome identifies novel prognostic DNA methylation signature in uveal melanoma.

Briefings in bioinformatics Jul 20, 2021
Uveal melanoma (UVM) is the most common primary intraocular human malignancy with a high mortality rate. Aberrant DNA methylation has rapidly emerged as a diagnostic and prognostic signature in many cancers. However, such DNA methylation signature av...
Female Melanoma Humans Machine Learning Neoplasm Proteins Predictive Value of Tests Male Middle Aged Gene Expression Regulation, Neoplastic DNA Methylation Gene Expression Profiling Disease-Free Survival Transcriptome Adult Uveal Neoplasms Aged DNA, Neoplasm Survival Rate Uveal Melanoma Aged, 80 and over
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