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Yttrium Radioisotopes

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Accurate brain age prediction with lightweight deep neural networks.

Medical image analysis
Deep learning has huge potential for accurate disease prediction with neuroimaging data, but the prediction performance is often limited by training-dataset size and computing memory requirements. To address this, we propose a deep convolutional neur...

A deep-learning-based prediction model for the biodistribution of Y microspheres in liver radioembolization.

Medical physics
BACKGROUND: Radioembolization with Y microspheres is a treatment approach for liver cancer. Currently, employed dosimetric calculations exhibit low accuracy, lacking consideration of individual patient, and tissue characteristics.

Using Deep Learning to Predict Treatment Response in Patients with Hepatocellular Carcinoma Treated with Y90 Radiation Segmentectomy.

Journal of digital imaging
Treatment of hepatocellular carcinoma (HCC) with Y90 radioembolization segmentectomy (Y90-RE) demonstrates a tumor dose-response threshold, where dose estimates are highly dependent on accurate SPECT/CT acquisition, registration, and reconstruction. ...

The role of biomarkers and dosimetry parameters in overall and progression free survival prediction for patients treated with personalized Y glass microspheres SIRT: a preliminary machine learning study.

European journal of nuclear medicine and molecular imaging
BACKGROUND: Overall Survival (OS) and Progression-Free Survival (PFS) analyses are crucial metrics for evaluating the efficacy and impact of treatment. This study evaluated the role of clinical biomarkers and dosimetry parameters on survival outcomes...

Deep Learning-Based Auto-Segmentation for Liver Yttrium-90 Selective Internal Radiation Therapy.

Technology in cancer research & treatment
The aim was to evaluate a deep learning-based auto-segmentation method for liver delineation in Y-90 selective internal radiation therapy (SIRT). A deep learning (DL)-based liver segmentation model using the U-Net3D architecture was built. Auto-segme...

Prediction of hepatocellular carcinoma response to radiation segmentectomy using an MRI-based machine learning approach.

Abdominal radiology (New York)
PURPOSE: To evaluate the value of pre-treatment MRI-based radiomics in patients with hepatocellular carcinoma (HCC) for the prediction of response to Yttrium 90 radiation segmentectomy.